MuScle-logoMuScle - Molecule ID B0207

geneACAP2, CENTB2
nameARF-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACAP2_HUMANQ15057ENSG0000011433123527Hs.593373607766

Functions and classifications

GOC:endosome membrane, F:ARF GTPase activator activity, F:zinc ion binding, P:cellular response to nerve growth factor stimulus, P:positive regulation of GTPase activity, P:protein localization to endosome, P:regulation of ARF GTPase activity, F:metal ion binding, F:phospholipid binding
UniProtANK repeat, Coiled coil, Complete proteome, Endosome, GTPase activation, Membrane, Metal-binding, Phosphoprotein, Reference proteome, Repeat, Zinc, Zinc-finger
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.844.61E-0222021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.187.10E-0322021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.423.57E-0522021740
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.310.045344522252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.646.29E-0422252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.662.99E-0222252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.821.82E-0223895517

Compile date 09-07-2016© MuScle project