MuScle-logoMuScle - Molecule ID B0205

geneACADVL, VLCAD
nameAcyl-CoA dehydrogenase, very-long-chain specific, mitochondrial precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACADV_HUMANP49748ENSG0000007277837Hs.437178201475, 609575

Functions and classifications

GOC:mitochondrial inner membrane, C:mitochondrial nucleoid, F:flavin adenine dinucleotide binding, F:long-chain-acyl-CoA dehydrogenase activity, P:activation of signaling protein activity involved in unfolded protein response, P:cellular protein metabolic process, P:energy derivation by oxidation of organic compounds, P:fatty acid beta-oxidation using acyl-CoA dehydrogenase, P:negative regulation of fatty acid biosynthetic process, P:negative regulation of fatty acid oxidation, P:regulation of cholesterol metabolic process, P:temperature homeostasis, F:acyl-CoA dehydrogenase activity, C:mitochondrion, F:fatty-acyl-CoA binding, F:very-long-chain-acyl-CoA dehydrogenase activity, P:very long-chain fatty acid catabolic process
UniProt3D-structure, Acetylation, Alternative splicing, Cardiomyopathy, Complete proteome, Disease mutation, FAD, Fatty acid metabolism, Flavoprotein, Isopeptide bond, Lipid metabolism, Membrane, Mitochondrion, Mitochondrion inner membrane, Oxidoreductase, Polymorphism, Reference proteome, S-nitrosylation, Transit peptide, Ubl conjugation
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)0.611.52E-0221886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.302.45E-0422021740
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.123.19E-0223895517

Compile date 09-07-2016© MuScle project