MuScle-logoMuScle - Molecule ID B0203

geneACADM, MCAD
nameAcyl-CoA dehydrogenase, medium-chain specific, mitochondrial precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACADM_HUMANP11310ENSG0000011705434Hs.445040201450, 607008

Functions and classifications

GOC:axon, C:mitochondrial matrix, F:flavin adenine dinucleotide binding, F:identical protein binding, F:medium-chain-acyl-CoA dehydrogenase activity, P:cardiac muscle cell differentiation, P:carnitine biosynthetic process, P:carnitine metabolic process, CoA-linked, P:fatty acid beta-oxidation using acyl-CoA dehydrogenase, P:glycogen biosynthetic process, P:liver development, P:medium-chain fatty acid catabolic process, P:post-embryonic development, P:regulation of gluconeogenesis, P:response to cold, P:response to starvation, F:acyl-CoA dehydrogenase activity, "F:flavin adenine dinucleotide binding, F:oxidoreductase activity, acting on the CH-CH group of donors", C:mitochondrion, "F:oxidoreductase activity, acting on the CH-CH group of donors", "C:mitochondrion, P:medium-chain fatty acid metabolic process, C:mitochondrial membrane, F:fatty-acyl-CoA binding, F:isomerase activity, P:protein homotetramerization, P:response to copper ion, P:response to drug, P:response to glucocorticoid stimulus, P:response to nutrient, "C:mitochondrial matrix
UniProt3D-structure, Acetylation, Alternative splicing, Complete proteome, Direct protein sequencing, Disease mutation, FAD, Fatty acid metabolism, Flavoprotein, Lipid metabolism, Mitochondrion, Oxidoreductase, Polymorphism, Reference proteome, Transit peptide
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.263.77E-0221886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)1.360.0165921886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.871.29E-0222021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)2.161.19E-0622252466

Compile date 09-07-2016© MuScle project