MuScle-logoMuScle - Molecule ID B0199

geneACACB, ACC2, ACCB
nameAcetyl-CoA carboxylase 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACACB_HUMANO00763ENSG0000007655532Hs.234898601557

Functions and classifications

GOC:cytosol, C:endomembrane system, C:membrane, C:mitochondrion, F:acetyl-CoA carboxylase activity, F:ATP binding, F:biotin binding, F:biotin carboxylase activity, F:metal ion binding, P:acetyl-CoA metabolic process, P:biotin metabolic process, P:carnitine shuttle, P:cellular lipid metabolic process, P:energy reserve metabolic process, P:fatty acid biosynthetic process, P:malonyl-CoA biosynthetic process, P:positive regulation of cellular metabolic process, P:protein homotetramerization, P:response to drug, P:response to organic cyclic compound, C:cytoplasm, P:regulation of fatty acid oxidation, P:small molecule metabolic process
UniProt3D-structure, Allosteric enzyme, Alternative splicing, ATP-binding, Biotin, Complete proteome, Fatty acid biosynthesis, Fatty acid metabolism, Ligase, Lipid biosynthesis, Lipid metabolism, Manganese, Membrane, Metal-binding, Multifunctional enzyme, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)1.711.65E-0217467740
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_2_days_follow-up) (Multiple sclerosis)1.430.0258169420136355
Exp20921521Homo sapiens10Blood PPMS_(PRF1_gene_Risk_haplotype) (Multiple sclerosis)2.100.010121420921521
Exp20921521Homo sapiens10Blood PPMS_(PRF1_gene_Risk_haplotype) (Multiple sclerosis)2.270.005574520921521
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)0.462.35E-0221886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)0.512.44E-0221886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)0.624.16E-0221886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_3_month_follow-up) (Multiple sclerosis)0.820.037515321886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.751.29E-0422021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.852.16E-0222021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.233.04E-0322252466
Exp22491253Homo sapiens7Blood RRMS_(Low_Sema4A) (Multiple sclerosis)0.260.000383622491253

Compile date 09-07-2016© MuScle project