MuScle-logoMuScle - Molecule ID B0188

geneABL2, ABLL, ARG
nameTyrosine-protein kinase ABL2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABL2_HUMANP42684ENSG0000014332227Hs.159472164690

Functions and classifications

GOC:actin cytoskeleton, C:cytosol, F:actin filament binding, F:actin monomer binding, F:ATP binding, F:magnesium ion binding, F:manganese ion binding, F:non-membrane spanning protein tyrosine kinase activity, P:actin filament bundle assembly, P:axon guidance, P:cell adhesion, P:cellular response to retinoic acid, P:positive regulation of neuron projection development, P:positive regulation of oxidoreductase activity, P:regulation of actin cytoskeleton reorganization, P:regulation of autophagy, P:regulation of cell adhesion, P:regulation of cell motility, P:regulation of endocytosis, P:signal transduction, P:peptidyl-tyrosine phosphorylation
UniProt3D-structure, Alternative splicing, ATP-binding, Cell adhesion, Complete proteome, Cytoplasm, Cytoskeleton, Kinase, Lipoprotein, Magnesium, Manganese, Metal-binding, Myristate, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, SH2 domain, SH3 domain, Transferase, Tyrosine-protein kinase, Ubl conjugation
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.163.86E-0222021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.202.53E-0222021740
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)1.224.35E-0222252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.636.95E-0622252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.443.37E-0522252466

Compile date 09-07-2016© MuScle project