MuScle-logoMuScle - Molecule ID B0185

geneABI2, ARGBPIA, ABI2B
nameAbl-interactor protein 2B
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABI2_HUMANQ9NYB9ENSG0000013844310152Hs.471156606442

Functions and classifications

GOC:cell-cell adherens junction, C:cytoskeleton, C:cytosol, C:dendrite, C:filopodium, C:lamellipodium, F:cytoskeletal adaptor activity, F:DNA binding, F:kinase binding, F:SH3 domain binding, P:actin polymerization or depolymerization, P:camera-type eye development, P:cell migration, P:dendrite development, P:learning or memory, P:peptidyl-tyrosine phosphorylation, C:cytoplasm, F:protein tyrosine kinase activator activity, P:positive regulation of protein tyrosine kinase activity
UniProt3D-structure, Alternative splicing, Cell projection, Coiled coil, Complete proteome, Cytoplasm, Cytoskeleton, Phosphoprotein, Reference proteome, SH3 domain
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.670.0128558720136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.870.0193535120136355
Exp20921521Homo sapiens10Blood PPMS_(PRF1_gene_Risk_haplotype) (Multiple sclerosis)1.470.020449320921521
Exp21346816Homo sapiens12Blood MS (Multiple sclerosis)1.180.01840521346816
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)0.533.27E-0221886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.611.68E-0422021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.871.74E-0222021740
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.290.022323322252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)2.933.24E-1122252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)4.035.86E-1022252466
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)1.750.0329263422491253
Exp22491253Homo sapiens7Blood RRMS_(Low_Sema4A) (Multiple sclerosis)0.230.000164422491253
Exp22491253Homo sapiens7Blood RRMS_(Low_Sema4A) (Multiple sclerosis)0.350.00689322491253
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.173.33E-0323895517

Compile date 09-07-2016© MuScle project