MuScle-logoMuScle - Molecule ID B0174

geneABHD5, NCIE2, CGI-58
name1-acylglycerol-3-phosphate O-acyltransferase ABHD5
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABHD5_HUMANQ8WTS1ENSG0000001119851099Hs.19385275630, 604780

Functions and classifications

GOC:cytosol, C:lipid particle, F:1-acylglycerol-3-phosphate O-acyltransferase activity, F:lysophosphatidic acid acyltransferase activity, P:cell differentiation, P:fatty acid metabolic process, P:negative regulation of sequestering of triglyceride, P:phosphatidic acid biosynthetic process, P:positive regulation of lipoprotein lipase activity, P:positive regulation of triglyceride catabolic process, P:small molecule metabolic process, P:triglyceride catabolic process, P:lipid metabolic process, F:hydrolase activity, P:metabolic process, F:peptidase activity, P:proteolysis
UniProtAcetylation, Acyltransferase, Cataract, Complete proteome, Cytoplasm, Deafness, Differentiation, Disease mutation, Fatty acid metabolism, Ichthyosis, Lipid biosynthesis, Lipid droplet, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism, Reference proteome, Transferase, Hydrolase
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20921521Homo sapiens10Blood PPMS_(PRF1_gene_Risk_haplotype) (Multiple sclerosis)1.350.0332520921521
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.273.00E-0322021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.469.42E-0422021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.186.60E-1122252466
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)0.550.0382299522491253

Compile date 09-07-2016© MuScle project