MuScle-logoMuScle - Molecule ID B0166

geneAPOBEC1
nameApolipoprotein B mRNA editing enzyme
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABEC1_HUMANP41238ENSG00000111701339Hs.560600130

Functions and classifications

GOC:cytoplasm, C:nucleoplasm, F:AU-rich element binding, F:cytidine deaminase activity, F:RNA binding, F:zinc ion binding, P:cellular response to insulin stimulus, P:cytidine to uridine editing, P:defense response to virus, P:DNA demethylation, P:lipid metabolic process, P:lipoprotein biosynthetic process, P:lipoprotein transport, P:mRNA modification, P:mRNA processing, P:mRNA stabilization, P:negative regulation of methylation-dependent chromatin silencing, P:regulation of cell proliferation, P:response to calcium ion, P:response to drug, P:response to ethanol, P:response to gamma radiation, P:response to osmotic stress, P:response to zinc ion, P:RNA processing, "F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines, P:metabolic process", F:metal ion binding, F:zinc ion binding"
UniProtComplete proteome, Cytoplasm, Hydrolase, Metal-binding, mRNA processing, Polymorphism, Reference proteome, Zinc
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10BloodRRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)2.022.71E-0217467740
Exp24850724Homo sapiens12BloodCIS (Multiple sclerosis)1.450.0311006624850724

Compile date 09-07-2016© MuScle project