MuScle-logoMuScle - Molecule ID B0164

geneABCG8
nameATP-binding cassette, sub-family G, member 8
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABCG8_HUMANQ9H221ENSG0000014392164241Hs.413931210250, 605460, 611465

Functions and classifications

GOC:apical plasma membrane, C:integral component of membrane, F:ATP binding, F:ATPase activity, F:sterol transporter activity, P:ATP catabolic process, P:cholesterol efflux, P:cholesterol homeostasis, P:excretion, P:intestinal cholesterol absorption, P:negative regulation of intestinal cholesterol absorption, P:negative regulation of intestinal phytosterol absorption, P:phospholipid transport, P:response to drug, P:response to nutrient, P:transmembrane transport, C:membrane, C:integral to membrane, P:lipid metabolic process, P:sterol transport
UniProtAlternative splicing, Complete proteome, Disease mutation, Glycoprotein, Membrane, Polymorphism, Reference proteome, Transmembrane, Transmembrane helix, Transport, ATP-binding, Nucleotide-binding
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50BloodRRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)1.669.59E-0320136355

Compile date 09-07-2016© MuScle project