MuScle-logoMuScle - Molecule ID B0149

geneABCC8, SUR1, SUR
nameSulfonylurea receptor 1
speciesHomo sapiens

Molecule reference

ABCC8_HUMANQ09428ENSG000000060716833Hs.54470240800, 256450, 600509, 602485, 606176, 610374

Functions and classifications

GOC:voltage-gated potassium channel complex, F:ATP binding, F:ATPase activity, coupled to transmembrane movement of substances, F:potassium ion transmembrane transporter activity, F:sulfonylurea receptor activity, P:ATP catabolic process, P:carbohydrate metabolic process, P:energy reserve metabolic process, P:regulation of insulin secretion, P:synaptic transmission, "C:integral component of membrane, P:potassium ion transport, P:signal transduction", P:ATP catabolic process", "C:sarcolemma, C:synaptic vesicle membrane, C:voltage-gated potassium channel complex, F:potassium channel activity, P:negative regulation of insulin secretion, P:positive regulation of potassium ion transport, P:response to drug, P:response to insulin stimulus, P:response to lipopolysaccharide, P:response to pH, P:response to zinc ion, "C:integral to membrane, P:potassium ion transport", F:ATPase activity, coupled to transmembrane movement of substances"
UniProtAlternative splicing, ATP-binding, Complete proteome, Diabetes mellitus, Disease mutation, Glycoprotein, Membrane, Nucleotide-binding, Polymorphism, Receptor, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Transport
PADBRCP: receptor

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.832.10E-0222252466

Compile date 09-07-2016© MuScle project