MuScle-logoMuScle - Molecule ID B0144

geneABCB6, MTABC3, PRP
nameATP-binding cassette half-transporter
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABCB6_HUMANQ9NP58ENSG0000011565710058Hs.107911111600, 605452, 614497

Functions and classifications

GOC:ATP-binding cassette (ABC) transporter complex, C:endoplasmic reticulum, C:Golgi apparatus, C:integral component of mitochondrial outer membrane, C:vacuolar membrane, F:ATP binding, F:efflux transmembrane transporter activity, F:heme binding, F:heme-transporting ATPase activity, P:brain development, P:cadmium ion transmembrane transport, P:cellular iron ion homeostasis, P:detoxification of cadmium ion, P:porphyrin-containing compound biosynthetic process, P:skin development, C:mitochondrion, C:integral to mitochondrial outer membrane, C:plasma membrane
UniProt3D-structure, Alternative splicing, ATP-binding, Cell membrane, Complete proteome, Disease mutation, Endoplasmic reticulum, Golgi apparatus, Membrane, Microphthalmia, Mitochondrion, Mitochondrion outer membrane, Nucleotide-binding, Polymorphism, Reference proteome, Transmembrane, Transmembrane helix, Transport
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)0.740.020714122252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)2.161.41E-0622252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)3.144.68E-0722252466

Compile date 09-07-2016© MuScle project