MuScle-logoMuScle - Molecule ID B0143

geneABCB5
nameATP-binding cassette sub-family B member 5
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABCB5_HUMANQ2M3G0ENSG00000004846340273Hs.404102611785

Functions and classifications

GOC:apical plasma membrane, C:Golgi membrane, C:integral component of plasma membrane, C:intercellular canaliculus, F:ATP binding, F:ATPase activity, coupled to transmembrane movement of substances, F:efflux transmembrane transporter activity, P:regulation of membrane potential, "C:integral component of membrane, P:ATP catabolic process", C:integral to plasma membrane, "C:integral to membrane, F:ATPase activity, coupled to transmembrane movement of substances"
UniProtAlternative splicing, ATP-binding, Cell membrane, Complete proteome, Membrane, Nucleotide-binding, Polymorphism, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Transport
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.524.43E-0320136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)1.332.41E-0220136355
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)0.863.10E-0222252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.951.84E-0223895517

Compile date 09-07-2016© MuScle project