MuScle-logoMuScle - Molecule ID B0137

geneABCA7, ABCA7/ABCA-SSN
nameATP-binding cassette sub-family A member 7
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABCA7_HUMANQ8IZY2ENSG0000006468710347Hs.134514605414

Functions and classifications

GOC:apical plasma membrane, C:ATP-binding cassette (ABC) transporter complex, C:endosome membrane, C:Golgi apparatus, C:Golgi membrane, C:integral component of membrane, F:ATP binding, F:ATPase activity, F:phospholipid transporter activity, F:transporter activity, P:ATP catabolic process, P:phagocytosis, P:phospholipid efflux, P:transmembrane transport, C:intracellular, C:integral to membrane, C:plasma membrane
UniProtAlternative splicing, ATP-binding, Cell membrane, Complete proteome, Disulfide bond, Endosome, Glycoprotein, Golgi apparatus, Membrane, Nucleotide-binding, Phagocytosis, Polymorphism, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Transport
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)0.583.81E-0321886806
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)0.730.013581822252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.591.32E-0222252466

Compile date 09-07-2016© MuScle project