MuScle-logoMuScle - Molecule ID B0135

geneABCA5
nameATP-binding cassette, sub-family A , member 5
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABCA5_HUMANQ8WWZ7ENSG0000015426523461Hs.731824612503

Functions and classifications

GOC:Golgi membrane, C:integral component of membrane, C:late endosome, C:late endosome membrane, C:lysosomal membrane, C:lysosome, F:ATP binding, F:ATPase activity, P:ATP catabolic process, P:cholesterol efflux, P:high-density lipoprotein particle remodeling, P:negative regulation of macrophage derived foam cell differentiation, P:reverse cholesterol transport, C:integral to membrane
UniProtAlternative splicing, ATP-binding, Complete proteome, Endosome, Glycoprotein, Golgi apparatus, Lysosome, Membrane, Nucleotide-binding, Polymorphism, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Transport
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)0.472.00E-0320136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.480.0029122420136355
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_12_month_follow-up) (Multiple sclerosis)0.690.0370153221886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.263.85E-0222021740
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)0.710.025971322252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)2.224.04E-0622252466

Compile date 09-07-2016© MuScle project