MuScle-logoMuScle - Molecule ID B0133

geneABCA3, ABCA3 variant protein, ABC3
nameATP-binding cassette, sub-family A, member 3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABCA3_HUMANQ99758ENSG0000016797221Hs.26630601615, 610921

Functions and classifications

GOC:alveolar lamellar body, C:alveolar lamellar body membrane, C:integral component of membrane, C:plasma membrane, F:ATP binding, F:ATPase activity, coupled to transmembrane movement of substances, P:response to drug, F:ATPase activity, P:ATP catabolic process, C:integral to membrane
UniProtATP-binding, Complete proteome, Disease mutation, Membrane, Nucleotide-binding, Polymorphism, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Transport
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.712.51E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)0.700.0234846620136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.730.0398924320136355
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)0.800.003739422252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)3.682.23E-1322252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.081.07E-0223895517

Compile date 09-07-2016© MuScle project