MuScle-logoMuScle - Molecule ID B0132

geneABCA2, ABC2
nameATP-binding cassette, sub-family A, member 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABCA2_HUMANQ9BZC7ENSG0000010733120Hs.421202600047

Functions and classifications

GOC:ATP-binding cassette (ABC) transporter complex, C:cytoplasmic membrane-bounded vesicle, C:endosome, C:endosome membrane, C:integral component of membrane, C:lysosomal membrane, C:lysosome, C:microtubule organizing center, F:ATP binding, F:ATPase activity, coupled to transmembrane movement of substances, P:cholesterol homeostasis, P:lipid metabolic process, P:regulation of intracellular cholesterol transport, P:regulation of transcription from RNA polymerase II promoter, P:response to drug, P:response to steroid hormone, F:ATPase activity, P:ATP catabolic process, C:integral to membrane, P:response to steroid hormone stimulus"
UniProtAlternative splicing, ATP-binding, Complete proteome, Endosome, Glycoprotein, Lysosome, Membrane, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Transport
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.873.24E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)0.860.0145031820136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.830.0107450720136355
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.793.38E-0222021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.633.88E-0722252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.266.90E-0323895517

Compile date 09-07-2016© MuScle project