MuScle-logoMuScle - Molecule ID B0128

geneAPOBEC3F, bK150C2.4
nameDNA DC->DU editing enzyme APOBEC-3F
speciesHomo sapiens

Molecule reference


Functions and classifications

GOC:apolipoprotein B mRNA editing enzyme complex, C:cytoplasmic mRNA processing body, F:cytidine deaminase activity, F:RNA binding, F:zinc ion binding, P:base conversion or substitution editing, P:defense response to virus, P:DNA cytosine deamination, P:DNA demethylation, P:innate immune response, P:negative regulation of single stranded viral RNA replication via double stranded DNA intermediate, P:negative regulation of transposition, P:positive regulation of defense response to virus by host, "F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines, P:metabolic process", C:cytoplasm, F:metal ion binding, P:negative regulation of retroviral genome replication
UniProt3D-structure, Alternative splicing, Antiviral defense, Complete proteome, Cytoplasm, Hydrolase, Immunity, Innate immunity, Metal-binding, Polymorphism, Reference proteome, Repeat, Zinc, Lipoprotein
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)1.285.80E-0320136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)1.274.12E-0220136355
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.757.77E-0322252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.402.07E-0223895517

Compile date 09-07-2016© MuScle project