MuScle-logoMuScle - Molecule ID B0126

geneAPOBEC3C, APOBEC1L, PBI
nameProbable DNA DC->DU-editing enzyme APOBEC-3C
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABC3C_HUMANQ9NRW3ENSG0000024450927350Hs.441124607750

Functions and classifications

GOC:cytoplasm, C:nucleus, F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines, F:zinc ion binding, P:cytidine deamination, P:defense response to virus, P:DNA demethylation, P:innate immune response, P:negative regulation of transposition, P:negative regulation of viral genome replication, P:viral process, "F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines, P:metabolic process", F:metal ion binding, P:virus-host interaction", P:metabolic process
UniProt3D-structure, Antiviral defense, Complete proteome, Cytoplasm, Host-virus interaction, Hydrolase, Immunity, Innate immunity, Metal-binding, Nucleus, Reference proteome, Zinc, Lipoprotein
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.712.21E-0322252466
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)1.870.0403270822491253
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.306.30E-0323895517

Compile date 09-07-2016© MuScle project