MuScle-logoMuScle - Molecule ID B0117

geneAATF, CHE1, DED
nameApoptosis antagonizing transcription factor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AATF_HUMANQ9NY61ENSG0000010827026574Hs.195740608463

Functions and classifications

GOC:centrosome, C:cytoplasm, C:focal adhesion, C:Golgi apparatus, C:nucleolus, F:sequence-specific DNA binding transcription factor activity, P:apoptotic signaling pathway, P:cell adhesion, P:cellular response to DNA damage stimulus, P:embryonic cleavage, P:negative regulation of amyloid precursor protein biosynthetic process, P:negative regulation of apoptotic process, P:negative regulation of superoxide anion generation, P:neurotrophin TRK receptor signaling pathway, P:positive regulation of apoptotic process, P:positive regulation of transcription from RNA polymerase II promoter, P:regulation of mitotic cell cycle, P:ribosome biogenesis, "C:centrosome, P:apoptotic process, P:nerve growth factor receptor signaling pathway, P:response to DNA damage stimulus, P:transcription, DNA-dependent"
UniProtAcetylation, Complete proteome, Nucleus, Phosphoprotein, Reference proteome
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.112.48E-0222021740
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)0.782.72E-0222252466

Compile date 09-07-2016© MuScle project