MuScle-logoMuScle - Molecule ID B0114

geneAASS, LKR/SDH
nameAlpha-aminoadipate semialdehyde synthase, mitochondrial
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AASS_HUMANQ9UDR5ENSG0000000831110157Hs.156738238700, 605113

Functions and classifications

GOC:mitochondrial matrix, F:saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity, F:saccharopine dehydrogenase (NADP+, L-lysine-forming) activity, P:cellular nitrogen compound metabolic process, P:L-lysine catabolic process to acetyl-CoA via saccharopine, P:lysine catabolic process, P:protein tetramerization, F:oxidoreductase activity, C:mitochondrion, "C:mitochondrion, P:L-lysine catabolic process", F:nucleotide binding, P:L-lysine catabolic process
UniProtAcetylation, Complete proteome, Mitochondrion, Multifunctional enzyme, NAD, NADP, Oxidoreductase, Reference proteome, Transit peptide
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.864.37E-0222021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)4.562.21E-1222252466

Compile date 09-07-2016© MuScle project