MuScle-logoMuScle - Molecule ID B0096

geneAACS, ACSF1, SUR5
nameAcetoacetyl-CoA synthetase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AACS_HUMANQ86V21ENSG0000008176065985Hs.656073614364

Functions and classifications

GOC:cytosol, F:acetoacetate-CoA ligase activity, F:ATP binding, F:butyrate-CoA ligase activity, P:adipose tissue development, P:cellular response to cholesterol, P:cellular response to glucose stimulus, P:cellular response to testosterone stimulus, P:fatty acid metabolic process, P:liver development, P:positive regulation of insulin secretion, P:response to drug, P:response to ethanol, P:response to nutrient, P:response to oleic acid, P:response to purine-containing compound, P:response to starvation, P:white fat cell differentiation, P:metabolic process, F:catalytic activity
UniProtAlternative splicing, ATP-binding, Complete proteome, Cytoplasm, Fatty acid metabolism, Ligase, Lipid metabolism, Nucleotide-binding, Polymorphism, Reference proteome, Phosphoprotein
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)0.780.0247102320136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_2_days_follow-up) (Multiple sclerosis)0.780.0170014120136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.770.0206899620136355
Exp21346816Homo sapiens12Blood MS (Multiple sclerosis)1.190.02786321346816
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.141.12E-0222021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)2.361.85E-0922252466

Compile date 09-07-2016© MuScle project