MoCadb-logoMoCadb - Study ID Exp24687888a

PubMed ID24687888
AuthorsKume H(1), Muraoka S(1), Kuga T(1), Adachi J(1), Narumi R(1), Watanabe S(1), Kuwano M(1), Kodera Y(2), Matsushita K(3), Fukuoka J(4), Masuda T(5), Ishihama Y(6), Matsubara H(7), Nomura F(3), Tomonaga T(8).
TitleDiscovery of colorectal cancer biomarker candidates by membrane proteomic analysis and subsequent verification using selected reaction monitoring (SRM) and tissue microarray (TMA) analysis.
JournalMol Cell Proteomics. 2014 Jun;13(6):1471-84.
AbstractRecent advances in quantitative proteomic technology have enabled the large-scale validation of biomarkers. We here performed a quantitative proteomic analysis of membrane fractions from colorectal cancer tissue to discover biomarker candidates, and then extensively validated the candidate proteins identified. A total of 5566 proteins were identified in six tissue samples, each of which was obtained from polyps and cancer with and without metastasis. GO cellular component analysis predicted that 3087 of these proteins were membrane proteins, whereas TMHMM algorithm predicted that 1567 proteins had a transmembrane domain. Differences were observed in the expression of 159 membrane proteins and 55 extracellular proteins between polyps and cancer without metastasis, while the expression of 32 membrane proteins and 17 extracellular proteins differed between cancer with and without metastasis. A total of 105 of these biomarker candidates were quantitated using selected (or multiple) reaction monitoring (SRM/MRM) with stable synthetic isotope-labeled peptides as an internal control. The results obtained revealed differences in the expression of 69 of these proteins, and this was subsequently verified in an independent set of patient samples (polyps (n = 10), cancer without metastasis (n = 10), cancer with metastasis (n = 10)). Significant differences were observed in the expression of 44 of these proteins, including ITGA5, GPRC5A, PDGFRB, and TFRC, which have already been shown to be overexpressed in colorectal cancer, as well as proteins with unknown function, such as C8orf55. The expression of C8orf55 was also shown to be high not only in colorectal cancer, but also in several cancer tissues using a multicancer tissue microarray, which included 1150 cores from 14 cancer tissues. This is the largest verification study of biomarker candidate membrane proteins to date; our methods for biomarker discovery and subsequent validation using SRM/MRM will contribute to the identification of useful biomarker candidates for various cancers. Data are available via ProteomeXchange with identifier PXD000851.

Sample characteristics

SpeciesTissue / SourceCompartmentDiseaseNDetection methodSample
Homo sapienspolyp_and_tumormembrane FractionsCRC without metastasis33LC-MS/MSDem4687888a, Dem4687888b

Sample description and preparation

N (case)17
N (control)16
Disease (case)CRC without metastasis
Disease (control)colorectal polyps
Preparation specific methodiTRAQ-labelling
Digestin-solution digestion, Trypsin
SeparationSCX column
Storage condition-80C

Sample analysis

Software analysis toolProteome Discoverer ver.1.3
Software thresholdP<0.1, fold change>2.0

Molecule list

Molecule IDextExternal IDGeneNameSource accRegulation (case/control)Scores
A0127 ABI1_HUMANABI1, SSH3BP, SSH3BP1Spectrin SH3 binding proteinQ8IZP0ratio: 0.459895607
A0420 ABLM1_HUMANABLIM1, ABLIM, LIMAB1Actin-binding LIM protein 1O14639ratio: 0.482557758
A5655 ACADM_HUMANACADM, MCADAcyl-CoA dehydrogenase, medium-chain specific, mitochondrial precursorP11310ratio: 0.471939973
A5656 ACADS_HUMANACADSAcyl-CoA dehydrogenase, short-chain specific, mitochondrial precursorP16219ratio: 0.440767888
A5700 ACSS3_HUMANACSS3Acyl-CoA synthetase short-chain family member 3 mitochondrialQ9H6R3ratio: 0.433597224
A5728 ADH1G_HUMANADH3, ADH1CAlcohol dehydrogenase 1CP00326ratio: 0.29064769
A8650 AGR2_HUMANAGR2, AG2, UNQ515/PRO1030Secreted cement gland protein XAG-2 homologO95994ratio: 0.438022785
A5751 AK1BA_HUMANAKR1B10, AKR1B11Aldo-keto reductase family 1 member B10O60218ratio: 0.273093331
A0143 AKAP5_HUMANAKAP5, AKAP79A-kinase anchor protein 5P24588ratio: 0.4291008
A3585 AL1A1_HUMANALDH1A1, ALDC, ALDH1Aldehyde dehydrogenase 1A1P00352ratio: 0.443616895
A3599 AL1B1_HUMANALDH1B1, ALDH5, ALDHXAldehyde dehydrogenase X, mitochondrialP30837ratio: 0.498537156
A5773 ALDR_HUMANAKR1B1, ALDR1Aldose reductaseP15121ratio: 0.479426535
A5796 AMPE_HUMANENPEPGlutamyl aminopeptidaseQ07075ratio: 2.534653792
A5269 ANR17_HUMANANKRD17, GTAR, NY-BR-16Ankyrin repeat domain protein 17O75179ratio: 2.184191646
A8661 ANS1A_HUMANANKS1A, ANKS1, ODINAnkyrin repeat and SAM domain containing protein 1AQ92625ratio: 3.55556681
A4570 ANTR1_HUMANANTXR1, ATR, TEM8Anthrax toxin receptor 1 precursorQ9H6X2ratio: 2.980927326
A4574 ANX13_HUMANANXA13, ANX13Annexin A13P27216ratio: 0.371392517
A1715 APOA_HUMANAPOA, LPAApolipoprotein(A) precursorP08519ratio: 2.124165036
A810B APOA4_HUMANAPOA4, ApoA-IV, APOA-IVApolipoprotein A-IV precursorP06727ratio: 0.322297155
A1176 APOE_HUMANAPOEApolipoprotein E precursorP02649ratio: 2.714412995
A819B APOL3_HUMANAPOL3Apolipoprotein L3O95236ratio: 2.026905166
B0901 ARAID_HUMANATRAID, 42828, HSPC013Apoptosis related protein APR-3Q6UW56ratio: 2.002967913
A2394 ARAP1_HUMANARAP1, CENTD2Centaurin delta 2Q96P48ratio: 2.715333106
A560E AREG_HUMANAREG, SDGF, AREGBAmphiregulin precursorP15514ratio: 5.183982672
A0477 B2CL1_HUMANBCL2L1, BCL2L, BCLXApoptosis regulator Bcl-XQ07817ratio: 2.508474304
A0768 B3A2_HUMANSLC4A2, AE2, EPB3L1Anion exchange protein 2P04920ratio: 2.036394739
B1334 B3GN6_HUMANB3GNT6, BETA3GNT6, B3Gn-T6Beta-1,3-N-acetylglucosaminyltransferase 6Q6ZMB0ratio: 0.2601334
A5910 B4GN2_HUMANB4GALNT2, GALGT2Beta-1,4 N-acetylgalactosaminyltransferase 2Q8NHY0ratio: 0.213286732
B1424 BCAP_HUMANPIK3AP1, BCAPPhosphoinositide-3-kinase adaptor protein 1Q6ZUJ8ratio: 4.260112546
A0789 BCAS1_HUMANBCAS1, AIBC1, NABC1Breast carcinoma amplified sequence 1O75363ratio: 0.440206315
A5924 BGAT_HUMANABOHisto-blood group ABO system transferaseP16442ratio: 0.30346392
B1580 BORG5_HUMANCDC42EP1, BORG5, CEP1CDC42 effector protein 1Q00587ratio: 3.610306975
A5946 BST1_HUMANBST1ADP-ribosyl cyclase 2 precursorQ10588ratio: 3.159749732
A1736 C5AR1_HUMANC5AR1, C5AR, C5R1C5a anaphylatoxin chemotactic receptor 1P21730ratio: 2.222526853
B1807 CA210_HUMAN Putative uncharacterized protein C1ORF210Q8IVY1ratio: 0.462370652
A5960 CAH12_HUMANCA12Carbonic anhydrase 12O43570ratio: 0.411051783
A0008 CALM_HUMANCALM1, CALM2, CALM3CalmodulinP62158ratio: 0.465469038
B1938 CAN9_HUMANCAPN9, NCL4Calpain 9O14815ratio: 0.272302222
A6000 CBPB2_HUMANCPB2, PCPBCarboxypeptidase B2Q96IY4ratio: 2.91074235
A010D CCD93_HUMANCCDC93Coiled-coil domain-containing protein 93Q567U6ratio: 0.372817519
A021D CD177_HUMANCD177, NB1, PRV1CD177 antigenQ8N6Q3ratio: 2.451895421
A1123 CD34_HUMANCD34Hematopoietic progenitor cell antigen CD34 precursorP28906ratio: 2.834494122
A0448 CDK1_HUMANCDK1, CDC2, CDC28ACrll division cycle 2P06493ratio: 2.242384139
A4665 CEAM5_HUMANCEACAM5, CEACarcinoembryonic antigen-related cell adhesion molecule 5P06731ratio: 3.26785072
A4666 CEAM6_HUMANCEA, CEACAM6, NCACarcinoembryonic antigen-related cell adhesion molecule 6 precursorP40199ratio: 3.688517339
A039D CEAM8_HUMANCEACAM8, CGM6Carcinoembryonic antigen-related cell adhesion molecule 8 precursorP31997ratio: 2.196155943
B2720 CGAS_HUMANMB21D1Uncharacterized protein C6ORF150Q8N884ratio: 2.302518529
A291A CHM1A_HUMANCHMP1A, CHMP1, PCOLN3Chromatin modifying protein 1AQ9HD42ratio: 2.034412576
A868B CHM2B_HUMANCHMP2B, CGI-84Charged multivesicular body protein 2BQ9UQN3ratio: 2.024091657
A870B CHM4B_HUMANCHMP4B, SHAX1, SNF7-2Charged multivesicular body protein 4BQ9H444ratio: 2.980526621
A6057 CHSS2_HUMANCHPF, CSS2, UNQ651/PRO1281Chondroitin sulfate synthase 2Q8IZ52ratio: 2.396435839
A138D CK083_HUMANUNQ655, UNQ655/PRO1286UPF0723 protein C11orf83Q6UW78ratio: 2.161351203
B2985 CKLF3_HUMANCMTM3, CKLFSF3CKLF-like MARVEL transmembrane domain-containing protein 3Q96MX0ratio: 3.19217404
A878B CLCA1_HUMANCLCA1, CACC1, HCLCA1Chloride channel, calcium activated, family member 1 precursorA8K7I4ratio: 0.141733549
A0087 CLD1_HUMANCLDN1, CLD1, SEMP1Claudin-1O95832ratio: 3.471806302
A6076 CLYBL_HUMANCLYBL, CLBCitrate lyase beta like protein, mitochondrialQ8N0X4ratio: 0.454273729
A9841 CMGA_HUMANCHGAChromogranin A precursorP10645ratio: 0.361501421
A170D CN159_HUMANUNQ2439/PRO5000, PFTL2439, UNQ2439UPF0317 protein C14ORF159, mitochondrialQ7Z3D6ratio: 0.440337607
A1616 CO5_HUMANC5, CPAMD4Complement C5 precursorP01031ratio: 2.196822423
A1623 CO6_HUMANC6Complement component C6P13671ratio: 2.518439856
A1628 CO9_HUMANC9Complement component C9 precursorP02748ratio: 2.418741315
A181D COBL1_HUMANCOBLL1Cordon-bleu protein-like 1Q53SF7ratio: 3.172592737
A4099 COQ4_HUMANCOQ4, CGI-92Ubiquinone biosynthesis protein COQ4 homolog, mitochondrialQ9Y3A0ratio: 2.953110963
A395B CP062_HUMAN Esophageal cancer-associated proteinQ7Z3J2ratio: 0.464723441
A6169 CP39A_HUMANCYP39A1Cytochrome P450, family 39, subfamily A, polypeptide 1Q9NYL5ratio: 2.940928344
A6202 CPSM_HUMANCPS1, CPSICarbamoyl-phosphate synthase [ammonia], mitochondrial precursorP31327ratio: 0.265359061
A0125 CSKP_HUMANCASK, LIN2Peripheral plasma membrane protein CASKO14936ratio: 0.483156142
A4738 CTHR1_HUMANCTHRC1, UNQ762/PRO1550, UNQ762Collagen triple helix repeat-containing protein 1Q96CG8ratio: 2.153128798
A0089 CTNA1_HUMANCTNNA1Alpha-1 cateninP35221ratio: 0.467409037
B3966 CXB2_HUMANGJB2Gap junction beta-2 proteinP29033ratio: 2.141599496
A6234 CYBR1_HUMANCYBRD1, DCYTB, FRRS3Cytochrome B reductase 1Q53TN4ratio: 2.249744397
A1720 DAB2_HUMANDAB2, DOC2Disabled homolog 2P98082ratio: 0.447106636
A1614 DAF_HUMANCD55, DAF, CRComplement decay-accelerating factor precursorP08174ratio: 2.053072962
A2127 DC1I2_HUMANDYNC1I2, DNCI2, DNCIC2Dynein intermediate chain 2, cytosolicQ13409ratio: 0.475406379
A4746 DC1L2_HUMANDYNC1LI2, DNCLI2, LIC2Dynein light intermediate chain 2, cytosolicO43237ratio: 0.47446552
A0461 DDAH1_HUMANDDAH1, DDAHN(G),N(G)-dimethylarginine dimethylaminohydrolase 1O94760ratio: 0.486471502
B4254 DEF5_HUMANDEFA5, DEF5Defensin 5 precursorQ01523ratio: 0.057584063
A9870 DEF6_HUMANDEFA6, DEF6Defensin 6 precursorQ01524ratio: 0.176097601
B4287 DERL2_HUMANDERL2, DER2, FLANADerlin-2Q9GZP9ratio: 2.002286612
A3718 DHB2_HUMANHSD17B2, EDH17B2Estradiol 17 beta-dehydrogenase 2P37059ratio: 0.329420776
A2013 DHCR7_HUMANDHCR7, D7SR7-dehydrocholesterol reductaseQ9UBM7ratio: 2.115575684
A4297 DJC15_HUMANDNAJC15, DNAJD1, GIG22DNAJ homolog subfamily C member 15Q9Y5T4ratio: 2.282930605
A0015 DLG1_HUMANDLG1, SAP97Disks large homolog 1Q12959ratio: 0.44263453
A8610 DMB_HUMANHLA-DMB, DMB, RING7HLA class II histocompatibility antigen, DM beta chain precursorP28068ratio: 2.107310584
A4305 DNJB2_HUMANDNAJB2, HSJ1, HSPF3DnaJ homolog subfamily B member 2P25686ratio: 2.641068613
A6356 DPEP1_HUMANDPEP1, MDP, RDPMicrosomal dipeptidase precursorP16444ratio: 2.854490735
A4757 DSG3_HUMANDSG3, CDHF6Desmoglein 3 precursorP32926ratio: 4.536840701
A6379 DUOX2_HUMANDUOX2, LNOX2, THOX2Dual oxidase 2 precursorQ9NRD8ratio: 0.426781859
A4766 DYH3_HUMANDNAH3, DNAHC3BDynein heavy chain 3, axonemalQ8TD57ratio: 0.367125144
A3865 E41L3_HUMANEPB41L3, DAL1Band 4.1-like protein 3Q9Y2J2ratio: 0.493544735
A6403 EBP_HUMANEBP3-beta-hydroxysteroid-delta(8),delta(7)-isomeraseQ15125ratio: 2.063931193
A6406 ECH1_HUMANECH1Delta(3,5)-delta(2,4)-dienoyl-CoA isomerase, mitochondrial precursorQ13011ratio: 0.461400162
A318D ECHD3_HUMANECHDC3, PP1494, PP8332Enoyl coenzyme A hydratase domain containing 3Q96DC8ratio: 2.945995042
A6408 ECHM_HUMANECHS1Enoyl-CoA hydratase, mitochondrial precursorP30084ratio: 0.49019663
A951B EFC4B_HUMANEFCAB4B, CRACR2AEF-hand calcium-binding domain-containing protein 4BQ9BSW2ratio: 0.448810289
B4957 ELOV5_HUMANELOVL5, ELOVL2, PRO0530Elongation of very long chain fatty acids protein 5Q9NYP7ratio: 3.823194793
A2472 ENPP6_HUMANENPP6, UNQ1889/PRO4334, UNQ1889Ectonucleotide pyrophosphatase/phosphodiesterase 6Q6UWR7ratio: 0.33022597
B5093 EPHX4_HUMANEPHX4, ABHD7, EPHXRPEpoxide hydrolase 4Q8IUS5ratio: 2.289432252
A2012 ERG24_HUMANTM7SF2, ANG1Delta(14)-sterol reductaseO76062ratio: 3.844399007
A335D ES1_HUMANHES1, KNPIES1 protein homolog, mitochondrial precursorP30042ratio: 0.473812672
A6459 EST3_HUMANCES3, UNQ869/PRO1887, UNQ869Carboxylesterase 3Q6UWW8ratio: 0.40673062
A441B EVA1B_HUMANEVA1B, FAM176BTransmembrane protein C1ORF78Q9NVM1ratio: 2.078730893
A4795 EVPL_HUMANEVPLEnvoplakinQ92817ratio: 0.388786537
A411B F210B_HUMANFAM210BTransmembrane protein C20ORF108Q96KR6ratio: 2.389868768
A069F FA26E_HUMANFAM26EHypothetical proteinQ8N5C1ratio: 2.050149699
A458B FA73B_HUMANFAM73BFamily with sequence similarity 73, member BQ7L4E1ratio: 2.337995694
A421A FA98B_HUMANFAM98BFamily with sequence similarity 98, member BQ52LJ0ratio: 0.448839098
A451D FAKD3_HUMANFASTKD3, HSPC091FAST kinase domain-containing protein 3Q14CZ7ratio: 2.407263261
A8773 FARP2_HUMANFARP2, PLEKHC3FERM, RhoGEF and pleckstrin domain-containing protein 2O94887ratio: 0.433884975
A1676 FBLN2_HUMANFBLN2Fibulin-2 precursorP98095ratio: 2.196550871
A8774 FBLN3_HUMANEFEMP1, FBLN3, FBNLEGF-containing fibulin-like extracellular matrix protein 1 precursorQ12805ratio: 2.969329558
A4806 FBN1_HUMANFBN1, FBNFibrillin-1P35555ratio: 2.215507003
A9295 FCERG_HUMANFCER1GHigh affinity immunoglobulin epsilon receptor gamma-subunit precursorP30273ratio: 2.017021529
A9713 FCGBP_HUMANFCGBPIgG Fc binding proteinQ9Y6R7ratio: 0.225839258
A0991 FCGR1_HUMANFCGR1A, FCG1, FCGR1High affinity immunoglobulin gamma Fc receptor IP12314ratio: 2.066282713
A1467 FIBA_HUMANFGAFibrinogen alpha/alpha-E chain precursorP02671ratio: 2.639604366
A1493 FIBB_HUMANFGBFibrinogen beta chain precursorP02675ratio: 2.697095694
A1494 FIBG_HUMANFGG, PRO2061Fibrinogen gamma chain precursorP02679ratio: 2.674984543
A1466 FINC_HUMANFN1, FNFibronectinP02751ratio: 2.401873419
A0279 FKB10_HUMANFKBP10, FKBP65FK506 binding protein 10 precursorQ96AY3ratio: 2.10627354
A463B FR1L6_HUMANFER1L6FER-1-like protein 6Q2WGJ9ratio: 0.205136833
A6546 G3ST4_HUMANGAL3ST4, PP6968, GAL3ST-4Galactose-3-O-sulfotransferase 4Q96RP7ratio: 2.132117531
A6568 GALT8_HUMANGALNT8UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 8Q9NY28ratio: 0.341471236
A0061 GBG4_HUMANGNG4, GNGT4Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-4 subunitP50150ratio: 3.314928641
A456A GCFC2_HUMANGCFC2, GCF, TCF9GC-rich sequence DNA-binding factorP16383ratio: 2.420283216
A6578 GCST_HUMANAMT, GCSTAminomethyltransferase, mitochondrial precursorP48728ratio: 0.463825902
A1547 GDN_HUMANSERPINE2, PI7, PN1Glia derived Nexin precursorP07093ratio: 2.428209427
A1082 GGT5_HUMANGGT5, GGTLA1Gamma-glutamyltransferase 5 precursorP36269ratio: 2.28337476
A6617 GLYL1_HUMANGLYATL1, GNAT, GATF-CGlycine-N-acyltransferase-like protein 1Q969I3ratio: 2.329792716
A9923 GMFB_HUMANGMFBGlia maturation factor betaP60983ratio: 0.468017681
A6624 GMPR1_HUMANGMPR, GMPR1GMP reductase 1P36959ratio: 0.451288079
A9333 GPC6_HUMANGPC6, UNQ369/PRO705, UNQ369Glypican-6 precursorQ9Y625ratio: 2.313211059
A9340 GPR56_HUMANGPR56, TM7LN4, TM7XN1G protein-coupled receptor 56Q9Y653ratio: 2.201157067
A6643 GPX2_HUMANGPX2Glutathione peroxidase 2P18283ratio: 0.495617241
A512D GRAM3_HUMANGRAMD3, NS3TP2GRAM domain-containing protein 3Q96HH9ratio: 4.146505478
A012C GTR3_HUMANSLC2A3, GLUT3Solute carrier family 2, facilitated glucose transporter, member 3P11169ratio: 2.74363954
A479A H2A1B_HUMANHIST1H2AB, HIST1H2AE, H2AFMHistone H2A.aP04908ratio: 2.066264351
A1462 HAT1_HUMANHAT1, KAT1Histone acetyltransferase 1O14929ratio: 0.497573814
A6693 HCDH_HUMANHADH, HAD, HADHSCHydroxyacyl-coenzyme A dehydrogenase, mitochondrialQ16836ratio: 0.494934835
A532D HEBP2_HUMANHEBP2, SOULHeme-binding protein 2Q9Y5Z4ratio: 0.391489861
B7090 HEMK1_HUMANHEMK1, HEMKHEMK methyltransferase family member 1Q9Y5R4ratio: 0.475380881
A2634 HID1_HUMANHID1, DMC1UPF0663 transmembrane protein C17ORF28Q8IV36ratio: 0.483291791
A6730 HKDC1_HUMANHKDC1Putative Hexokinase HKDC1Q2TB90ratio: 3.597503926
A6733 HMCS2_HUMANHMGCS2Hydroxymethylglutaryl-CoA synthase, mitochondrial precursorP54868ratio: 0.375380067
A2006 HSP72_HUMANHSPA2Heat shock-related 70 kDa protein 2P54652ratio: 0.414032837
A4344 HSP7E_HUMANHSPA14, HSP60, HSP70L1Heat shock 70 kDa protein 14Q0VDF9ratio: 3.325591538
A4856 HSPB1_HUMANHSPB1, HSP27, HSP28Heat shock protein beta-1P04792ratio: 2.108236544
A548D IBP2_HUMANIGFBP2, BP2, IBP2Insulin-like growth factor-binding protein 2P18065ratio: 0.441502309
A575A IF2B3_HUMANIGF2BP3, IMP3, KOC1Insulin-like growth factor 2 mRNA-binding protein 3O00425ratio: 3.080193427
A554D IFIT5_HUMANIFIT5, RI58, ISG58Interferon-induced protein with tetratricopeptide repeats 5Q13325ratio: 2.361115161
A482B IFM3_HUMANIFITM3Interferon-induced transmembrane protein 3Q01628ratio: 2.039576526
A9941 IGBP1_HUMANIGBP1, IBP1Immunoglobulin-binding protein 1P78318ratio: 2.597936488
A1411 IGHA1_HUMANIGM, SNC73, IGHA1Ig alpha-1 chain C regionP01876ratio: 0.359431719
A1424 IGHA2_HUMANIGHA2, IGH@Ig alpha-2 chainP01877ratio: 0.25147852
A598A IMP3_HUMANMRPS4, IMP3, BRMS2U3 small nucleolar ribonucleoprotein protein IMP3Q9NV31ratio: 2.636716096
A6805 IPYR2_HUMANPPA2, HSPC124, SID6-306Inorganic pyrophosphatase 2, mitochondrial precursorQ9H2U2ratio: 0.480526893
A0213 IQGA1_HUMANIQGAP1Ras GTPase-activating-like protein IQGAP1P46940ratio: 0.497536579
A9720 IQGA2_HUMANIQGAP2Ras GTPase-activating-like protein IQGAP2Q13576ratio: 0.421946146
A8427 ISK1_HUMANSPINK1, PSTIPancreatic secretory trypsin inhibitor precursorP00995ratio: 0.418468426
A1691 ITA11_HUMANITGA11, MSTP018, MST018Integrin alpha-11 precursorQ9UKX5ratio: 3.225721237
A1438 ITA2B_HUMANITGA2B, GP2B, ITGABIntegrin alpha-IIb precursorP08514ratio: 2.076550864
A0474 ITA5_HUMANITGA5, FNRAIntegrin alpha-5 precursorP08648ratio: 2.59438751
A492B K1324_HUMANEIG121, UNQ2426/PRO4985, MABA1UPF0577 protein KIAA1324Q6UXG2ratio: 0.489866578
A0338 K1C20_HUMANKRT20Keratin, type I cytoskeletal 20P35900ratio: 0.473455188
A4879 K2C74_HUMANKRT74, K6IRS4, KB37Keratin 74Q7RTS7ratio: 0.411199694
A6831 KBL_HUMANGCAT, KBL2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial precursorO75600ratio: 0.448229029
A060F KIME_HUMANMVKMevalonate kinaseQ03426ratio: 3.02839726
A0311 KPCI_HUMANPRKCI, DXS1179EProtein kinase C, iota typeP41743ratio: 2.058506329
A1010 LAIR1_HUMANLAIR1, CD305Leukocyte-associated IG-like receptor 1 precursorQ6GTX8ratio: 2.647592349
A6888 LDHD_HUMANLDHDD-lactate dehydrogenase, mitochondrialQ86WU2ratio: 0.409411972
A6920 LEG10_HUMANLGALS10A, CLCEosinophil lysophospholipaseQ05315ratio: 0.32261499
A4942 LIMA1_HUMANLIMA1, EPLIN, SREBP3LIM domain and actin-binding protein 1Q9UHB6ratio: 0.34865923
A586E LIMK2_HUMANLIMK2, LIMK-2, LIMK2BLIM domain kinase 2P53671ratio: 2.543579022
A3900 LIN7C_HUMANLIN7C, MALS3, VELI3Protein LIN-7 homolog CQ9NUP9ratio: 0.466305196
A6904 LITD1_HUMANL1TD1, ECAT11Line-1 type transposase domain-containing protein 1Q5T7N2ratio: 0.318470786
B8951 LMBR1_HUMANLMBR1, DIF14Limb region 1 protein homologQ8WVP7ratio: 2.289787583
A6913 LOX15_HUMANALOX15, LOG15Arachidonate 15-lipoxygenaseP16050ratio: 0.368037545
B8994 LPAR1_HUMANLPAR1, EDG2, LPA1Lysophosphatidic acid receptor 1Q92633ratio: 0.44772504
A509B LRC15_HUMANLRRC15, LIBLeucine-rich repeat-containing protein 15Q8TF66ratio: 3.398107869
A8867 LTBP1_HUMANLTBP1Latent transforming growth factor beta binding protein 1 precursorQ14766ratio: 2.187732223
A4960 MAP7_HUMANMAP7, E-MAP-115, EMAP115EnsconsinQ14244ratio: 0.485128754
A104C MCFD2_HUMANMCFD2, SDNSFNeural stem cell derived neuronal survival proteinQ8NI22ratio: 0.298647446
A105C MELPH_HUMANMLPH, UNQ8200, SLAC2AMelanophilinQ9BV36ratio: 0.372825045
A2115 MEP50_HUMANWDR77, MEP50, WD45WD repeat domain 77Q9BQA1ratio: 0.45417298
A4970 MFAP2_HUMANMFAP2, MAGP1Microfibrillar-associated protein 2 precursorP55001ratio: 2.556115283
A2320 MICA2_HUMANMICAL2, MICAL2PV2, MICAL2PV1Microtubule associated monoxygenase, calponin and LIM domain containing 2O94851ratio: 3.410677267
B9778 MKRN2_HUMANMKRN2, RNF62, HSPC070Makorin 2Q9H000ratio: 2.095475976
A1781 MMP14_HUMANMMP14Matrix metalloproteinase-14 precursorP50281ratio: 2.185762201
A1529 MMP2_HUMANMMP2, CLG4A72 kDa type IV collagenase precursorP08253ratio: 3.019240013
A1654 MMP7_HUMANMMP7, MPSL1, PUMP1Matrilysin precursorP09237ratio: 8.898266401
A7051 MMSA_HUMANMMSADHA, ALDH6A1, MMSDHMethylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial precursorQ02252ratio: 0.402209199
A7053 MOCS3_HUMANMOCS3, UBA4Molybdenum cofactor synthesis protein 3O95396ratio: 2.976236278
B9864 MOGT2_HUMANMOGAT2, DC5, DGAT2L52-acylglycerol O-acyltransferase 2Q3SYC2ratio: 0.44641935
A9405 MRC2_HUMANMRC2, CLEC13E, ENDO180C-type mannose receptor 2Q9UBG0ratio: 2.154056402
A140C MRS2_HUMANMRS2, HPT, MRS2LMagnesium transporter MRS2L, mitochondrial precursorQ9HD23ratio: 3.302404015
BA019 MSMO1_HUMANSC4MOL, MSMO1, DESP4C-4 methyl sterol oxidaseQ15800ratio: 2.120646206
A7073 MTHFS_HUMANMTHFS5-formyltetrahydrofolate cyclo-ligaseP49914ratio: 2.704043349
A1815 MTP_HUMANMTP, MTTPMicrosomal triglyceride transfer protein, large subunit precursorP55157ratio: 7.575073257
A4992 MUC2_HUMANMUC2, mucin, MLPMucin 2 precursorQ02817ratio: 0.262685373
A8886 MUC4_HUMANMUC4Mucin 4Q99102ratio: 0.330200437
A2615 MUC5B_HUMANMUC5B, MUC5, MG1Mucin-5BQ9HC84ratio: 0.364215116
A8888 MX1_HUMANMX1, MxAInterferon-induced GTP-binding protein MX1P20591ratio: 2.837692543
A541B MXRA7_HUMANMXRA7, TMAP1, PS1TP1Matrix-remodelling associated protein 7P84157ratio: 2.819961078
A0874 MYD88_HUMANMYD88Myeloid differentiation primary response protein MyD88Q99836ratio: 3.220200407
A3961 MYH10_HUMANMYH10, SmembMyosin-10P35580ratio: 2.108533862
A176C MYO5B_HUMANMYO5BMyosin VbQ9ULV0ratio: 0.48062554
A177C MYO5C_HUMANMYO5C, HSPC089Unconventional myosin-VcQ9NQX4ratio: 0.468003328
A179C MYO7B_HUMANMYO7BMyosin VIIBQ6PIF6ratio: 0.492820331
A2387 MYO9A_HUMANMYO9A, MYR7Myosin-IXaB2RTY4ratio: 0.483151998
BA298 NADE_HUMANNADSYN1Glutamine-dependent NAD synthetaseQ6IA69ratio: 0.440704824
A006A NALP2_HUMANNALP2, PP1579, NLRP2NACHT-, LRR- and PYD-containing protein 2Q9NX02ratio: 0.356732696
A1163 NCDN_HUMANNCDNNeurochondrinQ9UBB6ratio: 2.181614985
A7149 NEP_HUMANMME, EPNNeprilysinP08473ratio: 2.006056157
A3887 NTRI_HUMANHNT, NTM, IGLON2Neurotrimin precursorQ9P121ratio: 2.150407856
A8907 NUB1_HUMANNUB1, NYREN18NEDD8 ultimate buster-1Q9Y5A7ratio: 3.278477673
A5571 NUCB2_HUMANNucb2, NUCB2, NEFANucleobindin 2 precursorP80303ratio: 0.480435765
A7222 OAS2_HUMANOAS22'-5'-oligoadenylate synthetase 2P29728ratio: 2.695757604
A542E OLFL1_HUMANOLFML1, UNQ564/PRO1126, UNQ564Olfactomedin-like protein 1 precursorQ6UWY5ratio: 0.414590497
A8914 OX2G_HUMANCD200, MOX1, MOX2OX-2 membrane glycoprotein precursorP41217ratio: 3.292467271
BB735 P3H3_HUMANLEPREL2, P3H3, BProlyl 3-hydroxylase 3Q8IVL6ratio: 2.011757844
A0458 P53_HUMANTP53, p53, P53Cellular tumor antigen p53P04637ratio: 7.219353339
A823A PABP2_HUMANPABPN1, PAB2, PABP2Poly(A) binding protein IIQ86U42ratio: 0.363537628
A0693 PACN3_HUMANPACSIN3Protein kinase C and casein kinase substrate in neurons protein 3Q9UKS6ratio: 3.5916211
A7274 PADI2_HUMANPADI2, PDI2Peptidylarginine deiminase type 2Q9Y2J8ratio: 0.422562573
A784D PALD_HUMANPALD1, PALDPaladinQ9ULE6ratio: 2.504879497
BB864 PAR10_HUMANPARP10Poly [ADP]-ribose polymerase 10Q53GL7ratio: 2.217167417
A7306 PBLD_HUMANPBLD, MAWBPPhenazine biosynthesis-like domain-containing proteinP30039ratio: 0.323174374
A3601 PCCA_HUMANPCCAPropionyl-CoA carboxylase alpha chain, mitochondrial precursorP05165ratio: 0.487727716
A3602 PCCB_HUMANPCCBPropionyl-CoA carboxylase beta chain, mitochondrial precursorP05166ratio: 0.434986604
A029F PCH2_HUMANTRIP13, PCH2Thyroid hormone receptor interactor 13Q15645ratio: 2.407715694
A838A PDCD4_HUMANPDCD4, H731Programmed cell death 4Q53EL6ratio: 0.427233648
A032A PDCD5_HUMANPDCD5, TFAR19Programmed cell death protein 5O14737ratio: 0.435045543
A035A PDCL3_HUMANPDCL3, VIAF1, PhLP2APhosducin-like protein 3Q9H2J4ratio: 0.299513576
A5069 PDLI1_HUMANPDLIM1, CLIM1, CLP36PDZ and LIM domain protein 1O00151ratio: 0.404240694
A7359 PERE_HUMANEPX, EPER, EPOEosinophil peroxidase precursorP11678ratio: 0.460794479
A0459 PERI_HUMANPRPH, NEF4, PRPH1PeripherinP41219ratio: 2.457566404
A0706 PGFRB_HUMANPDGFRB, CSF1R, PDGFRBeta-type platelet-derived growth factor receptor precursorP09619ratio: 2.37544396
A7380 PGPS1_HUMANPGS1CDP-diacylglycerol--glycerol-3-phosphate 3 phosphatidyltransferase, mitochondrialQ32NB8ratio: 2.172580907
A1322 PIGR_HUMANPIGRPolymeric immunoglobulin receptor precursorP01833ratio: 0.435914071
A807D PKHA6_HUMANPLEKHA6, PEPP3Pleckstrin homology domain containing, family A member 6Q9Y2H5ratio: 0.409203929
A7419 PLCB4_HUMANPLCB41-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4Q15147ratio: 0.249659446
A7422 PLCD1_HUMANPLCD11-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1P51178ratio: 0.279966733
A5434 PLIN2_HUMANADFP, PLIN2AdipophilinQ99541ratio: 2.692636279
A7434 PLOD2_HUMANPLOD2Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 precursorO00469ratio: 2.017654643
A3775 PM34_HUMANSLC25A17, PMP34Peroxisomal membrane protein PMP34O43808ratio: 2.094082627
A292C PO210_HUMANNUP210Nuclear pore membrane glycoprotein 210Q8TEM1ratio: 2.532074673
A7472 PPAP_HUMANACPPProstatic acid phosphatase precursorP15309ratio: 0.490389329
A0980 PPR3D_HUMANPPP1R3D, PPP1R6Protein phosphatase 1, regulatory subunit 3DO95685ratio: 3.447076525
A1701 PRG2_HUMANPRG2, MBPEosinophil granule major basic protein precursorP13727ratio: 0.483096631
A1683 PRTN3_HUMANPRTN3, MBNMyeloblastin precursorP24158ratio: 3.346137754
A7528 PSB2_HUMANPSMB2Proteasome subunit beta type 2P49721ratio: 0.496335736
A7531 PSB6_HUMANPSMB6, LMPY, YProteasome subunit beta type 6 precursorP28072ratio: 0.379254186
A7532 PSB7_HUMANPSMB7, ZProteasome (prosome, macropain) subunit, beta type, 7 precursorQ99436ratio: 0.443165449
A579B PX11A_HUMANPEX11A, PEX11Peroxisomal membrane protein 11AO75192ratio: 3.505475574
A583B PXMP4_HUMANPXMP4, PMP24Peroxisomal membrane protein 4Q9Y6I8ratio: 2.973122202
A217E RAB31_HUMANRAB31, RAB22BRas-related protein Rab-31Q13636ratio: 2.22999366
A325C RAB3B_HUMANRAB3BRas-related protein Rab-3BP20337ratio: 0.377320956
BD264 RAB42_HUMANRAB42RAS small GTPase, RAS type family protein 42Q8N4Z0ratio: 2.397030706
A9464 RAI3_HUMANGPRC5A, GPCR5A, RAI3Retinoic acid induced 3Q8NFJ5ratio: 3.987409372
A8990 RASL1_HUMANRASAL1, RASALRasGAP-activating-like protein 1O95294ratio: 0.40075339
A231E RCN3_HUMANRCN3, UNQ239/PRO272, UNQ239Reticulocalbin 3 precursorQ96D15ratio: 3.710783511
A3708 RDHE2_HUMANSDR16C5, RDHE2, RDH-E2Epidermal retinol dehydrogenase 2Q8N3Y7ratio: 0.355654236
A596E REG4_HUMANREG4, GISP, RELPRegenerating gene type IVQ9BYZ8ratio: 0.215701208
A9003 REP15_HUMANREP15RAB15 effector proteinQ6BDI9ratio: 0.21811128
A1076 RGAP1_HUMANRACGAP1, MGCRACGAPGTPase activating protein RACGAP1Q9H0H5ratio: 3.803825664
A1858 RHG35_HUMANARHGAP35, GRF1, GRLF1Glucocorticoid receptor DNA binding factor 1Q9NRY4ratio: 0.475621382
A9551 RL23A_HUMANRPL23A60S ribosomal protein L23aP62750ratio: 0.426488487
A9552 RL24_HUMANRPL2460S ribosomal protein L24P83731ratio: 0.459411143
A9569 RL36L_HUMANRPL36AL60S ribosomal protein L36A-likeQ969Q0ratio: 0.396217009
A9571 RL37A_HUMANRPL37A60S ribosomal protein L37AP61513ratio: 0.47779414
A3812 RL8_HUMANRPL860S ribosomal protein L8P62917ratio: 0.486762457
BD896 RN128_HUMANRNF128, GRAILRing finger protein 128Q8TEB7ratio: 2.597589667
BE047 RPC3_HUMANPOLR3C, RPC62RNA polymerase III subunit, DNA directed, 62kDQ9BUI4ratio: 0.347626679
A9632 RS15_HUMANRPS15, RIG40S ribosomal protein S15P62841ratio: 0.478666118
A9640 RS23_HUMANRPS2340S ribosomal protein S23P62266ratio: 0.441643121
A9648 RS28_HUMANRPS2840S ribosomal protein S28P62857ratio: 0.444807851
A274E S100P_HUMANS100P, S100ES-100P proteinP25815ratio: 0.291914528
A107A S10AC_HUMANS100A12Protein S100-A12P80511ratio: 3.277797879
A279E S10AE_HUMANS100A14, S100A15Protein S100-A14Q9HCY8ratio: 0.319576884
A280E S10AG_HUMANS100A16, S100F, AAG13S100 calcium-binding protein A16Q96FQ6ratio: 0.48361421
BE301 S15A3_HUMANSLC15A3, OCTP, PHT2Solute carrier family 15 member 3Q8IY34ratio: 2.390216068
A3767 S2533_HUMANSLC25A33Solute carrier family 25 member 33Q9BSK2ratio: 2.677309054
A3768 S2536_HUMANSLC25A36Solute carrier family 25 member 36Q96CQ1ratio: 2.141784135
A437C S39A4_HUMANSLC39A4, ZIP4Zinc transporter ZIP4Q6P5W5ratio: 4.353668124
A3481 S4A10_HUMANSLC4A10, NCBESodium-driven chloride bicarbonate exchangerQ6U841ratio: 0.305256061
A1597 SAMP_HUMANAPCS, PTX2Serum amyloid P-component precursorP02743ratio: 2.614266551
A463C SBP1_HUMANSELENBP1, SBPSelenium-binding protein 1Q13228ratio: 0.23013511
BE603 SC5A6_HUMANSLC5A6, SMVTSodium-dependent multivitamin transporterQ9Y289ratio: 2.025334573
BE613 SC65_HUMANLEPREL4, NOL55, SC65Synaptonemal complex protein SC65Q92791ratio: 3.013856791
A7780 SCD5_HUMANSCD5, ACOD4, SCD4Stearoyl-CoA desaturase 5Q86SK9ratio: 2.681167841
A7783 SCOT1_HUMANOXCT1, OXCT, SCOTSuccinyl-CoA:3-ketoacid-coenzyme A transferase, mitochondrial precursorP55809ratio: 0.464769393
A1158 SDC4_HUMANSDC4Syndecan-4 precursorP31431ratio: 2.163539962
BE737 SELK_HUMANSELK, HSPC030, HSPC297Selenoprotein KQ9Y6D0ratio: 2.332470526
A7792 SEPR_HUMANFAPSepraseQ12884ratio: 5.98497378
A502C SGMR1_HUMANSIGMAR1, OPRS1, SRBPSigma 1-type opoid receptorQ99720ratio: 2.186055674
A9050 SH3L3_HUMANSH3BGRL3, P1725SH3 domain-binding glutamic acid-rich-like protein 3Q9H299ratio: 0.365752883
A0934 SIA4C_HUMANSIAT4C, ST3GAL4, CGS23CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferaseQ11206ratio: 0.354573527
A7812 SIA7A_HUMANST6GALNAC1, SIAT7A, UNQ543/PRO848Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1Q9NSC7ratio: 0.368486754
A0825 SL9A2_HUMANNa? exchanger isoform NHE-2, SLC9A2, NHE2Sodium/hydrogen exchanger 2Q9UBY0ratio: 0.216758337
A0826 SL9A3_HUMANSLC9A3, NHE3Sodium/hydrogen exchanger 3P48764ratio: 0.275995129
BF073 SL9A9_HUMANSLC9A9, NHE9Sodium/hydrogen exchanger 9Q8IVB4ratio: 0.286141958
A1320 SNP29_HUMANSNAP29Synaptosomal-associated protein 29O95721ratio: 2.300511582
BF272 SNX21_HUMANSNX21, SNXL, PP3993Sorting nexin 21Q969T3ratio: 3.722693335
A8502 SPB5_HUMANSERPINB5, PI5Maspin precursorP36952ratio: 0.367780037
A1533 SPRC_HUMANSPARC, ONSPARC precursorP09486ratio: 2.138619794
A7878 ST1B1_HUMANSULT1B1, ST1B2, SULT1B2Thyroid hormone sulfotransferaseO43704ratio: 0.33633541
A7885 STALP_HUMANSTAMBPL1, AMSHLP, AMSH-LPAMSH-like proteaseQ96FJ0ratio: 0.34961669
A0719 STAT1_HUMANSTAT1Signal transducer and activator of transcription 1-alpha/betaP42224ratio: 2.224511717
BF761 STMN3_HUMANSTMN3, SCLIPStathmin 3Q9NZ72ratio: 5.647123501
A2118 STRN4_HUMANSTRN4, ZINStriatin 4Q9NRL3ratio: 0.458074787
A7900 SUCB2_HUMANSUCLG2Succinyl-CoA ligase [GDP-forming] beta-chain, mitochondrial precursorQ96I99ratio: 0.49644269
A2491 SULF1_HUMANSULF1Extracellular sulfatase Sulf-1 precursorQ8IWU6ratio: 2.281652551
A2490 SULF2_HUMANSULF2, UNQ559/PRO1120, UNQ559Extracellular sulfatase Sulf-2 precursorQ8IWU5ratio: 2.330437882
A616B SUSD2_HUMANSUSD2Sushi domain-containing protein 2Q9UGT4ratio: 2.459349651
A3905 SYT7_HUMANSYT7, PCANAP7Synaptotagmin-7O43581ratio: 3.550941934
A589C SYTL2_HUMANCHR11SYT, SYTL2, SGA72MSynaptotagmin-like protein 2Q9HCH5ratio: 0.472076501
A543E TAC2N_HUMANTC2N, MTAC2D1Membrane targeting tandem C2 domain containing protein 1Q8N9U0ratio: 0.367730955
A1818 TAP1_HUMANTAP1, TAP1*0102N, ABCB2Antigen peptide transporter 1Q03518ratio: 2.036775031
A1839 TAP2_HUMANTAP2, ABCB3, PSF2Antigen peptide transporter 2Q03519ratio: 2.067255625
A495E TBC31_HUMANTBC1D31, WDR67WD-repeat protein 67Q96DN5ratio: 2.728954781
A5208 TENS3_HUMANTNS3, TEM6, TENS1Tensin 3Q68CZ2ratio: 2.070775019
A5210 TFF3_HUMANTFF3, ITF, TFITrefoil factor 3 precursorQ07654ratio: 0.323228247
A9493 TFR1_HUMANTFRCTransferrin receptor protein 1P02786ratio: 2.183175183
A080D THEM6_HUMANTHEM6, DSCD75UPF0670 protein C8ORF55Q8WUY1ratio: 2.073208982
A599C THIOM_HUMANTXN2, TRX2Thioredoxin, mitochondrial precursorQ99757ratio: 0.284835909
A9108 THSD4_HUMANTHSD4, UNQ9334/PRO34005, UNQ9334Thrombospondin type-1 domain-containing protein 4Q6ZMP0ratio: 2.264644831
A1218 THY1_HUMANTHY1Thy-1 membrane glycoprotein precursorP04216ratio: 2.060577579
BG676 TM189_HUMANTMEM189, KUATransmembrane protein 189A5PLL7ratio: 2.200493658
BG739 TM39A_HUMANTMEM39ATransmembrane protein 39AQ9NV64ratio: 2.228514771
BG742 TM41A_HUMANTMEM41A, UNQ168/PRO194, UNQ168Transmembrane protein 41A precursorQ96HV5ratio: 2.043226111
A697B TMCC3_HUMANTMCC3Transmembrane and coiled-coil doamins protein 3Q9ULS5ratio: 2.0418461
A698B TMCO1_HUMANTMCO1, TMCC4, PNAS-10Transmembrane and coiled-coil domain-containing protein 1Q9UM00ratio: 2.244929146
A9121 TMM97_HUMANTMEM97, MAC30Transmembrane protein 97Q5BJF2ratio: 2.540877226
A168A TPPC9_HUMANTRAPPC9, NIBP, T1Trafficking protein particle complex subunit 9Q96Q05ratio: 0.393822522
BH176 TRIQK_HUMANTRIQKUPF0599 protein C8ORF83Q629K1ratio: 2.221271632
BH179 TRM1_HUMANTRMT1N(2),N(2)-dimethylguanosine tRNA methyltransferaseQ9NXH9ratio: 3.217892837
A728B TSN8_HUMANTSPAN8, TM4SF3Tetraspanin-8P19075ratio: 0.491718065
A5232 TSP2_HUMANTHBS2, TSP2Thrombospondin 2 precursorP35442ratio: 2.668762919
BH312 TT39A_HUMANTTC39A, DEME-6Tetratricopeptide repeat protein 39AQ5SRH9ratio: 0.236190086
A462E UBTD1_HUMANUBTD1Ubiquitin domain-containing protein 1Q9HAC8ratio: 2.14556293
BH777 VANG2_HUMANVANGL2, STB1Vang-like protein 2Q9ULK5ratio: 2.548736765
A9141 VAV2_HUMANVAV2Guanine nucleotide exchange factor VAV2P52735ratio: 2.259922154
A9763 VMA21_HUMANVMA21, MEAX, XMEAVacuolar ATPase assembly integral membrane protein VMA21Q3ZAQ7ratio: 2.029309701
A8190 VNN1_HUMANVNN1Vanin 1O95497ratio: 3.446251574
A746B VSI10_HUMANVSIG10IG-like domain-containing protein FLJ20674Q8N0Z9ratio: 0.391728905
A1471 VTNC_HUMANVTNVitronectin precursorP04004ratio: 2.506194401
A1075 WASF2_HUMANWASF2, WAVE2Wiskott-Aldrich syndrome protein family member 2Q9Y6W5ratio: 0.412617322
A8206 XRN1_HUMANXRN1, 42979DNA strand-exchange protein SEP1Q8IZH2ratio: 2.793393729
A8225 ZDHC9_HUMANZDHHC9, ZDHHC10, ZNF379Zinc finger DHHC domain containing protein 9Q9Y397ratio: 2.533633384
A1821 1A25_HUMANHLA-A, HLA-A*24, HLAHLA class I histocompatibility antigen, A-2 alpha chain precursorP05534ratio: 2.552412634
A1821 1A25_HUMANHLA-A, HLA-A*24, HLAHLA class I histocompatibility antigen, A-2 alpha chain precursorP16188ratio: 0.146614426
A1823 1B73_HUMANHLA-B, HLA-B*40, HLA-B*13HLA class I histocompatibility antigen, B-35 alpha chain precursorP30461ratio: 0.07447679
A1823 1B73_HUMANHLA-B, HLA-B*40, HLA-B*13HLA class I histocompatibility antigen, B-35 alpha chain precursorP30481ratio: 0.062178254
A1823 1B73_HUMANHLA-B, HLA-B*40, HLA-B*13HLA class I histocompatibility antigen, B-35 alpha chain precursorP30483ratio: 0.144864643
A1823 1B73_HUMANHLA-B, HLA-B*40, HLA-B*13HLA class I histocompatibility antigen, B-35 alpha chain precursorQ95365ratio: 0.195428533
A1824 1C05_HUMANHLA-C, MHC class I, HLA-CwMajor histocompatibility complex, class I, CP30504ratio: 0.339455607
A8616 DRA_HUMANHLA-DRA, HLA-DRA1HLA class II histocompatibility antigen, DR alpha chain precursorP01903ratio: 2.060985813
A8599 DRB5_HUMANHLA-DRbeta, HLA-DRB6*01, HLA-DRB1HLA class II histocompatibility antigen, DRB1-4 beta chain precursorP01911ratio: 23.42154567
A8599 DRB5_HUMANHLA-DRbeta, HLA-DRB6*01, HLA-DRB1HLA class II histocompatibility antigen, DRB1-4 beta chain precursorP20039ratio: 7.940404114
A8599 DRB5_HUMANHLA-DRbeta, HLA-DRB6*01, HLA-DRB1HLA class II histocompatibility antigen, DRB1-4 beta chain precursorQ30154ratio: 3.233326098
A8363 IGHM_HUMANIGHM, IgIg mu chain CP01871ratio: 0.384442412
A8272 IGJ_HUMANIGJ, IGCJImmunoglobulin J chainP01591ratio: 0.332247775
A5671 ACOD_HUMANSCD, PRO0998Acyl-CoA desaturaseO00767ratio: 3.569988232
A0429 ACON_HUMANACO2Aconitate hydratase, mitochondrial precursorQ99798ratio: 0.49887609
A5974 CAN5_HUMANCAPN5, NCL3Calpain 5O15484ratio: 0.448441713
A071F EKI1_HUMANETNK1, EKI1, EKIEthanolamine kinase 1Q9HBU6ratio: 0.46965078
A8416 ICAL_HUMANCASTCalpain inhibitorP20810ratio: 0.468911894
A0883 IRS2_HUMANIRS2, irs-2, IRS-2Insulin receptor substrate-2Q9Y4H2ratio: 8.357791014
A1472 ITB3_HUMANITGB3, GP3A, GPIIIAIntegrin beta-3 precursorP05106ratio: 2.134539085
A8868 LTBP2_HUMANLTBP2, LTBP-2, LTBP3Latent-transforming growth factor beta-binding protein 2Q14767ratio: 2.91498888
A9753 SPD2B_HUMANSH3PXD2B, FAD49, TKS4SH3 and PX domain-containing protein 2BA1X283ratio: 2.074090044
A729B TSN9_HUMANTSPAN9, NET5, NET-5Tetraspanin-9O75954ratio: 2.313959555
A9137 UFM1_HUMANUFM1, BM-002, UPF0185Ubiquitin-fold modifier 1P61960ratio: 0.285450627

Compile date 10-20-2017© .