MoCadb-logoMoCadb - Molecule ID B0427

geneAEN, pp12744, ISG20L1
nameApoptosis-enhancing nuclease
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AEN_HUMANQ8WTP8ENSG0000018102664782Hs.436102610177

Functions and classifications

GOC:nucleolus, C:nucleoplasm, F:exonuclease activity, F:nucleic acid binding, P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, P:response to ionizing radiation
UniProtAlternative splicing, Apoptosis, Complete proteome, DNA damage, Exonuclease, Hydrolase, Nuclease, Nucleus, Polymorphism, Reference proteome
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceDiseaseP-valueDetectionPubMed/DOI
Exp21716316Homo sapiens4colon_rectumColorectal cancer (CRC) (CRC)0.0116whole genome-microarray21716316

Compile date 10-20-2017© .