MoCadb-logoMoCadb - Molecule ID A8386

geneARRB2, ARB2, ARR2
nameBeta-arrestin 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARRB2_HUMANP32121ENSG00000141480409Hs.435811107941

Functions and classifications

GOC:basolateral plasma membrane, C:coated pit, C:cytosol, C:dendritic spine, C:endocytic vesicle, C:nucleus, C:plasma membrane, C:postsynaptic density, C:postsynaptic membrane, F:protein complex scaffold, P:adult walking behavior, P:apoptotic DNA fragmentation, P:brain development, P:cell chemotaxis, P:desensitization of G-protein coupled receptor protein signaling pathway by arrestin, P:detection of temperature stimulus involved in sensory perception of pain, P:follicle-stimulating hormone signaling pathway, P:G-protein coupled receptor internalization, P:negative regulation of GTPase activity, P:negative regulation of interleukin-1 beta production, P:negative regulation of interleukin-12 production, P:negative regulation of interleukin-6 production, P:negative regulation of natural killer cell mediated cytotoxicity, P:negative regulation of NF-kappaB transcription factor activity, P:negative regulation of protein ubiquitination, P:negative regulation of smooth muscle cell apoptotic process, P:negative regulation of toll-like receptor signaling pathway, P:negative regulation of tumor necrosis factor production, P:Notch signaling pathway, P:platelet activation, P:positive regulation of apoptotic process, P:positive regulation of calcium ion transport, P:positive regulation of DNA biosynthetic process, P:positive regulation of ERK1 and ERK2 cascade, P:positive regulation of peptidyl-tyrosine phosphorylation, P:positive regulation of protein kinase B signaling, P:positive regulation of protein ubiquitination, P:positive regulation of receptor internalization, P:positive regulation of release of cytochrome c from mitochondria, P:positive regulation of synaptic transmission, dopaminergic, P:proteasome-mediated ubiquitin-dependent protein catabolic process, P:protein transport, P:protein ubiquitination, P:regulation of androgen receptor signaling pathway, P:transcription from RNA polymerase II promoter, P:transforming growth factor beta receptor signaling pathway, P:signal transduction, C:cytoplasm, P:endocytosis, P:regulation of G-protein coupled receptor protein signaling pathway, C:coated pit, C:cytoplasmic membrane-bounded vesicle, C:cytoplasmic vesicle, P:positive regulation of protein kinase B signaling cascade, P:proteasomal ubiquitin-dependent protein catabolic process, P:regulation of protein phosphorylation, C:intracellular, P:regulation of G-protein coupled receptor protein signaling pathway, P:signal transduction
UniProtAlternative splicing, Cell membrane, Coated pit, Complete proteome, Cytoplasm, Cytoplasmic vesicle, Hydroxylation, Membrane, Nucleus, Phosphoprotein, Protein transport, Reference proteome, Signal transduction inhibitor, Transport, Ubl conjugation
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceDiseaseP-valueDetectionPubMed/DOI
Exp26245529bHomo sapiens26colon_rectumColorectal cancer (CRC) (CRC)0.002512668LC-MS/MS26245529

Compile date 10-20-2017© .