MoCadb-logoMoCadb - Molecule ID A8369

geneA1A, SERPINA1, AAT
nameAlpha-1-antitrypsin precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
A1AT_HUMANP01009ENSG000001972495265Hs.525557107400, 613490

Functions and classifications

GOC:endoplasmic reticulum, C:extracellular space, C:platelet alpha granule lumen, C:proteinaceous extracellular matrix, F:serine-type endopeptidase inhibitor activity, P:acute-phase response, P:platelet activation, P:platelet degranulation, P:regulation of proteolysis
UniProt3D-structure, Acute phase, Alternative splicing, Blood coagulation, Complete proteome, Direct protein sequencing, Endoplasmic reticulum, Extracellular matrix, Glycoprotein, Hemostasis, Polymorphism, Protease inhibitor, Reference proteome, Secreted, Serine protease inhibitor, Signal
PADBINH: inhibitor (protease, kinase, other enzymes, pathways)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21716316Homo sapiens4colon_rectum Colorectal cancer (CRC) (CRC) 0.0118whole genome-microarray21716316
Exp25540887bHomo sapiens26bloodplasmaColorectal cancer (CRC) (CRC)2.010.01LC/MS25540887
Exp26175278aHomo sapiens16colon_rectum CRC (Stage II) (CRC)0.602174391<0.05LC-MS/MS26175278
Exp26175278bHomo sapiens10colon_rectum CRC (Stage IIIA) (CRC)2.152425686<0.05LC-MS/MS26175278
Exp26175278cHomo sapiens14colon_rectum CRC (Stage IIIB) (CRC)2.152425686<0.05LC-MS/MS26175278
Exp26175278dHomo sapiens17colon_rectum CRC (Stage IIIC) (CRC)2.739854256<0.05LC-MS/MS26175278
Exp26245529aHomo sapiens26colon_rectum Adenoma (Adenoma) 2.41E-05LC-MS/MS26245529
Exp27492143aHomo sapiens30bloodserumAdenoma (Adenoma)4.490.0017LC-MS/MS27492143
Exp27492143bHomo sapiens30bloodserumColorectal cancer (CRC) (CRC)5.655.64E-10LC-MS/MS27492143
Exp27492143cHomo sapiens30bloodserumColorectal cancer (CRC) (CRC)2.611.32E-09LC-MS/MS27492143
Exp28622966Homo sapiens10colon_rectum CRC tumor (CRC)0.65<0.05LC-MS/MS28622966

Compile date 10-20-2017© .