MoCadb-logoMoCadb - Molecule ID A7979

geneACAA2
nameAcetyl-CoA acyltransferase 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
THIM_HUMANP42765ENSG0000016731510449Hs.200136604770

Functions and classifications

GOC:mitochondrial inner membrane, C:mitochondrion, F:acetyl-CoA C-acyltransferase activity, P:cholesterol biosynthetic process, P:fatty acid metabolic process, P:negative regulation of mitochondrial outer membrane permeabilization, F:transferase activity, transferring acyl groups other than amino-acyl groups, P:acetyl-CoA metabolic process, P:fatty acid beta-oxidation, P:negative regulation of apoptotic process
UniProtAcetylation, Acyltransferase, Complete proteome, Direct protein sequencing, Fatty acid metabolism, Lipid metabolism, Mitochondrion, Phosphoprotein, Polymorphism, Reference proteome, Transferase, Transit peptide
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21716316Homo sapiens4colon_rectum Colorectal cancer (CRC) (CRC) 0.000712whole genome-microarray21716316
Exp26861291aHomo sapiens20rectummicrodissected tissuenCRT I, Dworak 1 2 (poor responder) (CRC)n.r.<0.05LTQ-hybrid mass spectrometer26861291
Exp26861291bHomo sapiens20rectummicrodissected tissuenCRT II, Dworak 1 2 (poor responder) (CRC)0.48<0.05LTQ-hybrid mass spectrometer26861291

Compile date 10-20-2017© .