MoCadb-logoMoCadb - Molecule ID A6993

geneABCB1, MDR1, PGY1
nameMultidrug resistance protein 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
MDR1_HUMANP08183ENSG000000855635243Hs.489033171050, 612244, 120080

Functions and classifications

GOC:apical plasma membrane, C:cell surface, C:Golgi membrane, C:integral component of membrane, C:intercellular canaliculus, F:ATP binding, F:ATPase activity, coupled to transmembrane movement of substances, F:xenobiotic-transporting ATPase activity, P:drug transmembrane transport, P:G2/M transition of mitotic cell cycle, P:stem cell proliferation, P:xenobiotic transport, C:integral component of membrane, P:ATP catabolic process, F:ATPase activity, P:ATP catabolic process, C:integral to membrane, P:stem cell proliferation, C:integral to membrane
UniProtATP-binding, Cell membrane, Complete proteome, Glycoprotein, Hydrolase, Membrane, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Transport
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceDiseaseP-valueDetectionPubMed/DOI
Exp19969511Homo sapiens11rectumRectal cancer (RC) (RC)0.00161whole genome-microarray19969511
Exp21716316Homo sapiens4colon_rectumColorectal cancer (CRC) (CRC)0.0388whole genome-microarray21716316
Exp26245529aHomo sapiens26colon_rectumAdenoma (Adenoma)0.026637516LC-MS/MS26245529
Exp26245529cHomo sapiens8colon_rectumColorectal cancer (CRC) (CRC)0.014272064LC-MS/MS26245529

Compile date 10-20-2017© .