MoCadb-logoMoCadb - Molecule ID A6708

geneALAS2, ALASE, ASB
name5-aminolevulinate synthase 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
HEM0_HUMANP22557ENSG00000158578212Hs.522666300751, 300752, 301300

Functions and classifications

GOC:mitochondrial inner membrane, C:mitochondrial matrix, F:5-aminolevulinate synthase activity, F:coenzyme binding, F:glycine binding, F:pyridoxal phosphate binding, P:cellular iron ion homeostasis, P:erythrocyte differentiation, P:heme biosynthetic process, P:hemoglobin biosynthetic process, P:oxygen homeostasis, P:protoporphyrinogen IX biosynthetic process, P:response to hypoxia, P:small molecule metabolic process, F:catalytic activity, P:metabolic process, P:biosynthetic process, P:porphyrin-containing compound metabolic process, P:tetrapyrrole biosynthetic process, C:mitochondrion
UniProtAcyltransferase, Alternative splicing, Complete proteome, Disease mutation, Heme biosynthesis, Mitochondrion, Pyridoxal phosphate, Reference proteome, Transferase, Transit peptide
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceDiseaseP-valueDetectionPubMed/DOI
Exp19969511Homo sapiens11rectumRectal cancer (RC) (RC)0.00133whole genome-microarray19969511

Compile date 10-20-2017© .