MoCadb-logoMoCadb - Molecule ID A6374

geneADAR, ADAR1, DSRAD
nameDouble-stranded RNA-specific adenosine deaminase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
DSRAD_HUMANP55265ENSG00000160710103Hs.12341127400, 146920, 615010, 601059

Functions and classifications

GOC:cytoplasm, C:nucleolus, C:nucleoplasm, C:nucleus, C:supraspliceosomal complex, F:DNA binding, F:double-stranded RNA adenosine deaminase activity, F:metal ion binding, F:RNA binding, P:adenosine to inosine editing, P:defense response to virus, P:gene expression, P:gene silencing by RNA, P:mRNA modification, P:mRNA processing, P:negative regulation of apoptotic process, P:negative regulation of protein kinase activity by regulation of protein phosphorylation, P:positive regulation of viral genome replication, P:protein export from nucleus, P:protein import into nucleus, P:response to interferon-alpha, P:response to virus, P:type I interferon signaling pathway, P:RNA processing, F:double-stranded RNA binding, P:type I interferon-mediated signaling pathway, C:intracellular
UniProt3D-structure, Aicardi-Goutieres syndrome, Alternative promoter usage, Alternative splicing, Antiviral defense, Complete proteome, Cytoplasm, Direct protein sequencing, Disease mutation, DNA-binding, Hydrolase, Immunity, Innate immunity, Isopeptide bond, Metal-binding, mRNA processing, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Repeat, RNA-binding, RNA-mediated gene silencing, Ubl conjugation, Zinc
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceDiseaseP-valueDetectionPubMed/DOI
Exp26245529aHomo sapiens26colon_rectumAdenoma (Adenoma)0.034374283LC-MS/MS26245529
Exp26245529bHomo sapiens26colon_rectumColorectal cancer (CRC) (CRC)0.000732962LC-MS/MS26245529
Exp26245529cHomo sapiens8colon_rectumColorectal cancer (CRC) (CRC)0.001712175LC-MS/MS26245529

Compile date 10-20-2017© .