MoCadb-logoMoCadb - Molecule ID A5893

nameActivin receptor type IIB precursor
speciesHomo sapiens

Molecule reference

AVR2B_HUMANQ13705ENSG0000011473993Hs.174273602730, 613751

Functions and classifications

GOC:cytoplasm, C:integral component of plasma membrane, F:ATP binding, F:metal ion binding, F:protein serine/threonine kinase activity, F:protein serine/threonine/tyrosine kinase activity, F:receptor signaling protein serine/threonine kinase activity, F:transforming growth factor beta-activated receptor activity, P:activation of protein kinase activity, P:activin receptor signaling pathway, P:anterior/posterior pattern specification, P:artery development, P:blood vessel remodeling, P:BMP signaling pathway, P:determination of left/right symmetry, P:embryonic foregut morphogenesis, P:gastrulation with mouth forming second, P:heart development, P:insulin secretion, P:intracellular signal transduction, P:kidney development, P:lung development, P:lymphangiogenesis, P:lymphatic endothelial cell differentiation, P:mesoderm development, P:odontogenesis of dentin-containing tooth, P:organ growth, P:palate development, P:pancreas development, P:positive regulation of activin receptor signaling pathway, P:positive regulation of bone mineralization, P:positive regulation of osteoblast differentiation, P:post-embryonic development, P:response to glucose, P:retina vasculature development in camera-type eye, P:signal transduction by phosphorylation, P:skeletal system morphogenesis, P:venous blood vessel development, C:membrane, P:protein phosphorylation, P:regulation of signal transduction, P:transmembrane receptor protein serine/threonine kinase signaling pathway, C:cell surface, C:integral to plasma membrane, F:activin-activated receptor activity, P:response to glucose stimulus
UniProt3D-structure, Alternative splicing, ATP-binding, Cell membrane, Complete proteome, Disease mutation, Disulfide bond, Glycoprotein, Heterotaxy, Kinase, Magnesium, Manganese, Membrane, Metal-binding, Nucleotide-binding, Phosphoprotein, Polymorphism, Receptor, Reference proteome, Serine/threonine-protein kinase, Signal, Transferase, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceDiseaseP-valueDetectionPubMed/DOI
Exp21716316Homo sapiens4colon_rectumColorectal cancer (CRC) (CRC)0.00252whole genome-microarray21716316

Compile date 10-20-2017© .