MoCadb-logoMoCadb - Molecule ID A5773

geneAKR1B1, ALDR1
nameAldose reductase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ALDR_HUMANP15121ENSG00000085662231Hs.521212103880

Functions and classifications

GOC:cytosol, C:extracellular space, C:nucleus, F:alditol:NADP 1-oxidoreductase activity, F:electron carrier activity, F:glyceraldehyde oxidoreductase activity, P:C21-steroid hormone biosynthetic process, P:carbohydrate metabolic process, P:daunorubicin metabolic process, P:doxorubicin metabolic process, P:response to stress, P:oxidation-reduction process, F:oxidoreductase activity, C:cytoplasm, P:small molecule metabolic process
UniProt3D-structure, Acetylation, Complete proteome, Cytoplasm, Direct protein sequencing, NADP, Oxidoreductase, Polymorphism, Reference proteome
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21716316Homo sapiens4colon_rectum Colorectal cancer (CRC) (CRC) 0.0013whole genome-microarray21716316
Exp24687888aHomo sapiens33polyp_and_tumormembrane FractionsCRC without metastasis (CRC)0.479426535< 0.001LC-MS/MS24687888
Exp26245529aHomo sapiens26colon_rectum Adenoma (Adenoma) 3.22E-09LC-MS/MS26245529
Exp26245529cHomo sapiens8colon_rectum Colorectal cancer (CRC) (CRC) 0.010534136LC-MS/MS26245529

Compile date 10-20-2017© .