MoCadb-logoMoCadb - Molecule ID A5751

geneAKR1B10, AKR1B11
nameAldo-keto reductase family 1 member B10
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AK1BA_HUMANO60218ENSG0000019807457016Hs.116724604707

Functions and classifications

GOC:cytosol, C:extracellular region, C:lysosome, F:aldo-keto reductase (NADP) activity, F:geranylgeranyl reductase activity, F:indanol dehydrogenase activity, F:retinal dehydrogenase activity, P:cellular aldehyde metabolic process, P:daunorubicin metabolic process, P:digestion, P:doxorubicin metabolic process, P:farnesol catabolic process, P:phototransduction, visible light, P:retinoid metabolic process, P:steroid metabolic process, P:steroid metabolic process
UniProt3D-structure, Acetylation, Complete proteome, Lysosome, NADP, Oxidoreductase, Polymorphism, Reference proteome, Secreted
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19969511Homo sapiens11rectum Rectal cancer (RC) (RC) 0.000223whole genome-microarray19969511
Exp21716316Homo sapiens4colon_rectum Colorectal cancer (CRC) (CRC) 0.000129whole genome-microarray21716316
Exp24687888aHomo sapiens33polyp_and_tumormembrane FractionsCRC without metastasis (CRC)0.273093331< 0.001LC-MS/MS24687888
Exp24687888bHomo sapiens32polyp_and_tumormembrane FractionsCRC metastasis (CRC)0.281858797< 0.001LC-MS/MS24687888
Exp26175278aHomo sapiens16colon_rectum CRC (Stage II) (CRC)1.38542521<0.05LC-MS/MS26175278
Exp26175278bHomo sapiens10colon_rectum CRC (Stage IIIA) (CRC)3.887693008<0.05LC-MS/MS26175278
Exp26175278cHomo sapiens14colon_rectum CRC (Stage IIIB) (CRC)3.887693008<0.05LC-MS/MS26175278
Exp26175278dHomo sapiens17colon_rectum CRC (Stage IIIC) (CRC)12.01083914<0.05LC-MS/MS26175278
Exp26245529bHomo sapiens26colon_rectum Colorectal cancer (CRC) (CRC) 3.26E-07LC-MS/MS26245529
Exp26245529cHomo sapiens8colon_rectum Colorectal cancer (CRC) (CRC) 0.000171147LC-MS/MS26245529

Compile date 10-20-2017© .