MoCadb-logoMoCadb - Molecule ID A5702

nameSerine/threonine-protein kinase receptor R3 precursor
speciesHomo sapiens

Molecule reference

ACVL1_HUMANP37023ENSG0000013956794Hs.591026600376, 601284

Functions and classifications

GOC:cell surface, C:dendrite, C:integral component of plasma membrane, C:neuronal cell body, F:activin binding, F:activin receptor activity, type I, F:ATP binding, F:metal ion binding, F:receptor signaling protein serine/threonine kinase activity, F:SMAD binding, F:transforming growth factor beta receptor activity, type I, F:transforming growth factor beta-activated receptor activity, P:artery development, P:blood vessel endothelial cell proliferation involved in sprouting angiogenesis, P:blood vessel maturation, P:blood vessel remodeling, P:BMP signaling pathway, P:cellular response to BMP stimulus, P:endothelial tube morphogenesis, P:in utero embryonic development, P:intracellular signal transduction, P:lymphangiogenesis, P:lymphatic endothelial cell differentiation, P:negative regulation of blood vessel endothelial cell migration, P:negative regulation of cell growth, P:negative regulation of cell proliferation, P:negative regulation of DNA biosynthetic process, P:negative regulation of endothelial cell differentiation, P:negative regulation of endothelial cell proliferation, P:negative regulation of focal adhesion assembly, P:positive regulation of BMP signaling pathway, P:positive regulation of chondrocyte differentiation, P:positive regulation of endothelial cell differentiation, P:positive regulation of endothelial cell proliferation, P:positive regulation of pathway-restricted SMAD protein phosphorylation, P:positive regulation of transcription from RNA polymerase II promoter, P:protein heterooligomerization, P:regulation of blood pressure, P:regulation of DNA replication, P:regulation of endothelial cell proliferation, P:retina vasculature development in camera-type eye, P:transforming growth factor beta receptor signaling pathway, P:venous blood vessel development, P:wound healing, spreading of epidermal cells, C:membrane, P:signal transduction by phosphorylation, C:dendrite, P:angiogenesis, P:positive regulation of transcription, DNA-templated, P:venous blood vessel development, F:protein kinase activity, F:protein serine/threonine kinase activity, P:transmembrane receptor protein serine/threonine kinase signaling pathway, P:protein phosphorylation, C:integral to plasma membrane, F:transmembrane receptor protein serine/threonine kinase activity
UniProt3D-structure, Angiogenesis, ATP-binding, Complete proteome, Disease mutation, Disulfide bond, Glycoprotein, Kinase, Magnesium, Manganese, Membrane, Metal-binding, Nucleotide-binding, Phosphoprotein, Polymorphism, Receptor, Reference proteome, Serine/threonine-protein kinase, Signal, Transferase, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceDiseaseP-valueDetectionPubMed/DOI
Exp19969511Homo sapiens11rectumRectal cancer (RC) (RC)0.000446whole genome-microarray19969511
Exp21716316Homo sapiens4colon_rectumColorectal cancer (CRC) (CRC)0.000777whole genome-microarray21716316

Compile date 10-20-2017© .