MoCadb-logoMoCadb - Molecule ID A5657

geneACADVL, VLCAD
nameAcyl-CoA dehydrogenase, very-long-chain specific, mitochondrial precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACADV_HUMANP49748ENSG0000007277837Hs.437178201475, 609575

Functions and classifications

GOC:mitochondrial inner membrane, C:mitochondrial nucleoid, F:flavin adenine dinucleotide binding, F:long-chain-acyl-CoA dehydrogenase activity, P:activation of signaling protein activity involved in unfolded protein response, P:cellular protein metabolic process, P:energy derivation by oxidation of organic compounds, P:fatty acid beta-oxidation using acyl-CoA dehydrogenase, P:negative regulation of fatty acid biosynthetic process, P:negative regulation of fatty acid oxidation, P:regulation of cholesterol metabolic process, P:temperature homeostasis, F:acyl-CoA dehydrogenase activity, C:mitochondrion, F:fatty-acyl-CoA binding, F:very-long-chain-acyl-CoA dehydrogenase activity, P:very long-chain fatty acid catabolic process
UniProt3D-structure, Acetylation, Alternative splicing, Cardiomyopathy, Complete proteome, Disease mutation, FAD, Fatty acid metabolism, Flavoprotein, Isopeptide bond, Lipid metabolism, Membrane, Mitochondrion, Mitochondrion inner membrane, Oxidoreductase, Polymorphism, Reference proteome, S-nitrosylation, Transit peptide, Ubl conjugation
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26175278aHomo sapiens16colon_rectumCRC (Stage II) (CRC)1.692152302<0.05LC-MS/MS26175278
Exp26175278bHomo sapiens10colon_rectumCRC (Stage IIIA) (CRC)2.417225281<0.05LC-MS/MS26175278
Exp26175278cHomo sapiens14colon_rectumCRC (Stage IIIB) (CRC)2.417225281<0.05LC-MS/MS26175278
Exp26175278dHomo sapiens17colon_rectumCRC (Stage IIIC) (CRC)3.082459291<0.05LC-MS/MS26175278
Exp26245529bHomo sapiens26colon_rectumColorectal cancer (CRC) (CRC) 0.001934077LC-MS/MS26245529
Exp26245529cHomo sapiens8colon_rectumColorectal cancer (CRC) (CRC) 0.000591523LC-MS/MS26245529
Exp28622966Homo sapiens10colon_rectumCRC tumor (CRC)0.63<0.05LC-MS/MS28622966

Compile date 10-20-2017© .