MoCadb-logoMoCadb - Molecule ID A5655

geneACADM, MCAD
nameAcyl-CoA dehydrogenase, medium-chain specific, mitochondrial precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACADM_HUMANP11310ENSG0000011705434Hs.445040201450, 607008

Functions and classifications

GOC:axon, C:mitochondrial matrix, F:flavin adenine dinucleotide binding, F:identical protein binding, F:medium-chain-acyl-CoA dehydrogenase activity, P:cardiac muscle cell differentiation, P:carnitine biosynthetic process, P:carnitine metabolic process, CoA-linked, P:fatty acid beta-oxidation using acyl-CoA dehydrogenase, P:glycogen biosynthetic process, P:liver development, P:medium-chain fatty acid catabolic process, P:post-embryonic development, P:regulation of gluconeogenesis, P:response to cold, P:response to starvation, F:acyl-CoA dehydrogenase activity, F:flavin adenine dinucleotide binding, F:oxidoreductase activity, acting on the CH-CH group of donors, C:mitochondrion, F:oxidoreductase activity, acting on the CH-CH group of donors, C:mitochondrion, P:medium-chain fatty acid metabolic process, C:mitochondrial membrane, F:fatty-acyl-CoA binding, F:isomerase activity, P:protein homotetramerization, P:response to copper ion, P:response to drug, P:response to glucocorticoid stimulus, P:response to nutrient, C:mitochondrial matrix
UniProt3D-structure, Acetylation, Alternative splicing, Complete proteome, Direct protein sequencing, Disease mutation, FAD, Fatty acid metabolism, Flavoprotein, Lipid metabolism, Mitochondrion, Oxidoreductase, Polymorphism, Reference proteome, Transit peptide
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21716316Homo sapiens4colon_rectum Colorectal cancer (CRC) (CRC) 0.00495whole genome-microarray21716316
Exp24687888aHomo sapiens33polyp_and_tumormembrane FractionsCRC without metastasis (CRC)0.4719399730.00844548LC-MS/MS24687888
Exp26245529bHomo sapiens26colon_rectum Colorectal cancer (CRC) (CRC) 0.011860288LC-MS/MS26245529
Exp26245529cHomo sapiens8colon_rectum Colorectal cancer (CRC) (CRC) 0.001090696LC-MS/MS26245529

Compile date 10-20-2017© .