MoCadb-logoMoCadb - Molecule ID A5632

geneAADAT, KAT2
nameL-kynurenine/alpha-aminoadipate aminotransferase, mitochondrial precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AADAT_HUMANQ8N5Z0ENSG0000010957651166Hs.529735611754

Functions and classifications

GOC:mitochondrial matrix, F:2-aminoadipate transaminase activity, F:kynurenine-oxoglutarate transaminase activity, F:pyridoxal phosphate binding, P:2-oxoglutarate metabolic process, P:biosynthetic process, P:glutamate metabolic process, P:L-lysine catabolic process to acetyl-CoA via saccharopine, P:lysine catabolic process, P:tryptophan catabolic process, P:tryptophan catabolic process to kynurenine, F:catalytic activity, C:mitochondrion, F:transaminase activity
UniProt3D-structure, Acetylation, Alternative splicing, Aminotransferase, Complete proteome, Mitochondrion, Polymorphism, Pyridoxal phosphate, Reference proteome, Transferase, Transit peptide
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseP-valueDetectionPubMed/DOI
Exp17717129Homo sapiens20bloodplasmaColorectal cancer (CRC) (CRC)0.01208506cDNA microarray17717129
Exp17717129Homo sapiens20bloodplasmaColorectal cancer (CRC) (CRC)0.04084273cDNA microarray17717129
Exp19969511Homo sapiens11rectum Rectal cancer (RC) (RC)0.000379whole genome-microarray19969511

Compile date 10-20-2017© .