MoCadb-logoMoCadb - Molecule ID A4562

geneAIF1, G1, IBA1
nameAllograft inflammatory factor-1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AIF1_HUMANP55008ENSG00000204472199Hs.76364601833

Functions and classifications

GOC:actin filament, C:cytosol, C:lamellipodium, C:nucleus, C:perinuclear region of cytoplasm, C:phagocytic cup, C:ruffle membrane, F:actin filament binding, F:calcium ion binding, P:actin filament bundle assembly, P:actin filament polymerization, P:cellular response to interferon-gamma, P:inflammatory response, P:microglial cell activation, P:negative regulation of smooth muscle cell chemotaxis, P:negative regulation of smooth muscle cell proliferation, P:phagocytosis, engulfment, P:positive regulation of G1/S transition of mitotic cell cycle, P:positive regulation of monocyte chemotaxis, P:positive regulation of smooth muscle cell chemotaxis, P:positive regulation of smooth muscle cell proliferation, P:positive regulation of T cell migration, P:positive regulation of T cell proliferation, P:Rac protein signal transduction, P:ruffle assembly, C:cytoplasm, P:ruffle assembly, C:perikaryon, P:cellular response to extracellular stimulus, P:cellular response to hormone stimulus, P:negative regulation of apoptotic process, P:negative regulation of gene expression, P:positive regulation of muscle hyperplasia, P:positive regulation of nitric oxide biosynthetic process, P:positive regulation of protein phosphorylation, P:response to axon injury, P:response to electrical stimulus, C:ruffle, P:positive regulation of cell migration, P:response to cytokine stimulus
UniProt3D-structure, Acetylation, Actin-binding, Alternative splicing, Calcium, Cell membrane, Cell projection, Complete proteome, Cytoplasm, Cytoskeleton, Membrane, Metal-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceDiseaseP-valueDetectionPubMed/DOI
Exp21716316Homo sapiens4colon_rectumColorectal cancer (CRC) (CRC)0.00048whole genome-microarray21716316
Exp21716316Homo sapiens4colon_rectumColorectal cancer (CRC) (CRC)0.0027whole genome-microarray21716316
Exp26245529aHomo sapiens26colon_rectumAdenoma (Adenoma)0.017460899LC-MS/MS26245529
Exp26245529bHomo sapiens26colon_rectumColorectal cancer (CRC) (CRC)0.000998306LC-MS/MS26245529
Exp26245529cHomo sapiens8colon_rectumColorectal cancer (CRC) (CRC)0.003021111LC-MS/MS26245529

Compile date 10-20-2017© .