MoCadb-logoMoCadb - Molecule ID A4555

geneACTA1, ACTA
nameActin, alpha skeletal muscle
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACTS_HUMANP68133ENSG0000014363258Hs.1288102610, 161800, 255310

Functions and classifications

GOC:actin filament, C:cytosol, C:extracellular vesicular exosome, C:stress fiber, C:striated muscle thin filament, F:ADP binding, F:ATP binding, F:myosin binding, F:structural constituent of cytoskeleton, P:cell growth, P:muscle filament sliding, P:response to extracellular stimulus, P:response to lithium ion, P:response to mechanical stimulus, P:response to steroid hormone, P:skeletal muscle fiber adaptation, P:skeletal muscle fiber development, P:skeletal muscle thin filament assembly, C:cytoplasm, C:cytoskeleton, P:response to steroid hormone stimulus
UniProt3D-structure, Acetylation, ATP-binding, Complete proteome, Cytoplasm, Cytoskeleton, Disease mutation, Methylation, Muscle protein, Nemaline myopathy, Nucleotide-binding, Oxidation, Reference proteome, Phosphoprotein
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26054784Homo sapiens8colon_rectum CRC tumor (CRC)11.843380.008010394Nano-LC–MS/MS26054784
Exp26861291aHomo sapiens20rectummicrodissected tissuenCRT I, Dworak 1 2 (poor responder) (CRC)n.r.<0.05LTQ-hybrid mass spectrometer26861291
Exp26861291bHomo sapiens20rectummicrodissected tissuenCRT II, Dworak 1 2 (poor responder) (CRC)0.19<0.05LTQ-hybrid mass spectrometer26861291

Compile date 10-20-2017© .