MoCadb-logoMoCadb - Molecule ID A4552

geneACTG1, ACTG
nameActin, cytoplasmic 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACTG_HUMANP63261ENSG0000018400971Hs.514581102560, 604717, 614583

Functions and classifications

GOC:cytoskeleton, C:cytosol, C:extracellular vesicular exosome, C:filamentous actin, C:myofibril, F:ATP binding, F:structural constituent of cytoskeleton, P:adherens junction organization, P:axon guidance, P:cell junction assembly, P:Fc-gamma receptor signaling pathway involved in phagocytosis, P:innate immune response, P:sarcomere organization, C:cytoplasm, C:axon, C:cortical cytoskeleton, C:postsynaptic density, P:axonogenesis, P:blood coagulation, P:cellular component movement, P:response to calcium ion
UniProtAcetylation, ATP-binding, Complete proteome, Cytoplasm, Cytoskeleton, Deafness, Direct protein sequencing, Disease mutation, Mental retardation, Methylation, Non-syndromic deafness, Nucleotide-binding, Oxidation, Polymorphism, Reference proteome, Phosphoprotein
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26245529aHomo sapiens26colon_rectum Adenoma (Adenoma) 0.000156053LC-MS/MS26245529
Exp26245529cHomo sapiens8colon_rectum Colorectal cancer (CRC) (CRC) 0.039316759LC-MS/MS26245529
Exp26861291aHomo sapiens20rectummicrodissected tissuenCRT I, Dworak 1 2 (poor responder) (CRC)n.r.<0.05LTQ-hybrid mass spectrometer26861291
Exp26861291bHomo sapiens20rectummicrodissected tissuenCRT II, Dworak 1 2 (poor responder) (CRC)0.45<0.05LTQ-hybrid mass spectrometer26861291

Compile date 10-20-2017© .