MoCadb-logoMoCadb - Molecule ID A4551

geneACTC1, ACTC
nameActin, alpha cardiac muscle 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACTC_HUMANP68032ENSG0000015925170Hs.118127102540, 612098, 612794, 613424

Functions and classifications

GOC:actomyosin, actin portion, C:cytosol, C:extracellular vesicular exosome, C:I band, F:ATP binding, F:ATPase activity, F:myosin binding, P:apoptotic process, P:cardiac muscle contraction, P:cardiac muscle tissue morphogenesis, P:cardiac myofibril assembly, P:heart contraction, P:muscle filament sliding, P:negative regulation of apoptotic process, P:response to drug, P:response to ethanol, P:skeletal muscle thin filament assembly, C:actin cytoskeleton, C:smooth muscle contractile fiber, P:regulation of blood pressure, P:skeletal muscle thin filament assembly, P:vascular smooth muscle contraction, C:cytoplasm, C:cytoskeleton, C:actomyosin, actin part
UniProtAcetylation, ATP-binding, Atrial septal defect, Cardiomyopathy, Complete proteome, Cytoplasm, Cytoskeleton, Disease mutation, Methylation, Muscle protein, Nucleotide-binding, Oxidation, Reference proteome
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp25540887bHomo sapiens26bloodplasmaColorectal cancer (CRC) (CRC)3.350.003LC/MS25540887
Exp26861291aHomo sapiens20rectummicrodissected tissuenCRT I, Dworak 1 2 (poor responder) (CRC)n.r.<0.05LTQ-hybrid mass spectrometer26861291
Exp26861291bHomo sapiens20rectummicrodissected tissuenCRT II, Dworak 1 2 (poor responder) (CRC)0.29<0.05LTQ-hybrid mass spectrometer26861291

Compile date 10-20-2017© .