MoCadb-logoMoCadb - Molecule ID A4548

geneACTB, PS1TP5BP1
nameActin, cytoplasmic 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACTB_HUMANP60709ENSG0000007562460Hs.520640102630, 243310, 607371

Functions and classifications

GOC:axon, C:cortical cytoskeleton, C:cytoskeleton, C:cytosol, C:extracellular vesicular exosome, C:MLL5-L complex, C:NuA4 histone acetyltransferase complex, C:postsynaptic density, C:ribonucleoprotein complex, F:ATP binding, F:structural constituent of cytoskeleton, P:'de novo' posttranslational protein folding, P:adherens junction organization, P:axon guidance, P:blood coagulation, P:cell junction assembly, P:Fc-gamma receptor signaling pathway involved in phagocytosis, P:innate immune response, C:cytoplasm, C:filamentous actin, C:myofibril, P:axonogenesis, P:sarcomere organization, C:protein complex, P:cellular component movement, P:response to calcium ion
UniProt3D-structure, Acetylation, ATP-binding, Complete proteome, Cytoplasm, Cytoskeleton, Deafness, Direct protein sequencing, Disease mutation, Dystonia, Mental retardation, Methylation, Nucleotide-binding, Oxidation, Polymorphism, Reference proteome, Ubl conjugation
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp25540887bHomo sapiens26bloodplasmaColorectal cancer (CRC) (CRC)3.360.002LC/MS25540887
Exp26861291aHomo sapiens20rectummicrodissected tissuenCRT I, Dworak 1 2 (poor responder) (CRC)n.r.<0.05LTQ-hybrid mass spectrometer26861291
Exp26861291bHomo sapiens20rectummicrodissected tissuenCRT II, Dworak 1 2 (poor responder) (CRC)0.57<0.05LTQ-hybrid mass spectrometer26861291
Exp27492143aHomo sapiens30bloodserumAdenoma (Adenoma)7.050.05LC-MS/MS27492143
Exp27492143bHomo sapiens30bloodserumColorectal cancer (CRC) (CRC)7.870.01LC-MS/MS27492143
Exp27492143cHomo sapiens30bloodserumColorectal cancer (CRC) (CRC)1.460.09LC-MS/MS27492143

Compile date 10-20-2017© .