MoCadb-logoMoCadb - Molecule ID A4547

geneACTA2, ACTSA, ACTVS
nameActin, aortic smooth muscle
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACTA_HUMANP62736ENSG0000010779659Hs.500483102620, 611788, 613834, 614042

Functions and classifications

GOC:actin cytoskeleton, C:cytosol, C:protein complex, C:smooth muscle contractile fiber, F:ATP binding, P:glomerular mesangial cell development, P:muscle contraction, P:regulation of blood pressure, P:response to virus, P:vascular smooth muscle contraction, C:cell periphery, C:cytoplasm, C:cytoskeleton
UniProtAcetylation, Aortic aneurysm, ATP-binding, Complete proteome, Cytoplasm, Cytoskeleton, Disease mutation, Methylation, Muscle protein, Nucleotide-binding, Oxidation, Polymorphism, Reference proteome
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26245529aHomo sapiens26colon_rectum Adenoma (Adenoma) 2.83E-05LC-MS/MS26245529
Exp26245529bHomo sapiens26colon_rectum Colorectal cancer (CRC) (CRC) 0.001502849LC-MS/MS26245529
Exp26245529cHomo sapiens8colon_rectum Colorectal cancer (CRC) (CRC) 7.10E-05LC-MS/MS26245529
Exp26861291aHomo sapiens20rectummicrodissected tissuenCRT I, Dworak 1 2 (poor responder) (CRC)n.r.<0.05LTQ-hybrid mass spectrometer26861291
Exp26861291bHomo sapiens20rectummicrodissected tissuenCRT II, Dworak 1 2 (poor responder) (CRC)0.58<0.05LTQ-hybrid mass spectrometer26861291
Exp27468721Homo sapiens10colon_rectum Colorectal cancer (CRC) (CRC) <0.05LC-MS/MS27468721

Compile date 10-20-2017© .