MoCadb-logoMoCadb - Molecule ID A3494

geneAGRN, AGRIN
nameAgrin
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AGRIN_HUMANO00468ENSG00000188157375790Hs.273330103320, 254300

Functions and classifications

GOC:basal lamina, C:cell junction, C:cell surface, C:extracellular space, C:Golgi lumen, C:integral component of membrane, C:lysosomal lumen, C:plasma membrane, C:synapse, F:acetylcholine receptor regulator activity, F:calcium ion binding, F:chondroitin sulfate binding, F:dystroglycan binding, F:heparan sulfate proteoglycan binding, F:laminin binding, F:sialic acid binding, F:structural constituent of cytoskeleton, P:axon guidance, P:carbohydrate metabolic process, P:chondroitin sulfate metabolic process, P:clustering of voltage-gated sodium channels, P:extracellular matrix organization, P:G-protein coupled acetylcholine receptor signaling pathway, P:glycosaminoglycan biosynthetic process, P:glycosaminoglycan catabolic process, P:neuromuscular junction development, P:neurotransmitter receptor metabolic process, P:phototransduction, visible light, P:plasma membrane organization, P:positive regulation of filopodium assembly, P:positive regulation of neuron apoptotic process, P:positive regulation of Rho GTPase activity, P:positive regulation of synaptic growth at neuromuscular junction, P:positive regulation of transcription from RNA polymerase II promoter, P:receptor clustering, P:regulation of receptor activity, P:retinoid metabolic process, P:synapse organization, C:basal lamina, P:positive regulation of protein geranylgeranylation, P:positive regulation of protein phosphorylation, P:regulation of Rac GTPase activity, P:synapse assembly, P:synapse organization
UniProtAlternative splicing, Calcium, Cell junction, Cell membrane, Complete proteome, Congenital myasthenic syndrome, Developmental protein, Differentiation, Disease mutation, Disulfide bond, EGF-like domain, Extracellular matrix, Glycoprotein, Heparan sulfate, Laminin EGF-like domain, Membrane, Polymorphism, Proteoglycan, Reference proteome, Repeat, Secreted, Signal, Synapse, Transmembrane, Transmembrane helix
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseP-valueDetectionPubMed/DOI
Exp17717129Homo sapiens20bloodplasmaColorectal cancer (CRC) (CRC)0.00936348cDNA microarray17717129

Compile date 10-20-2017© .