MoCadb-logoMoCadb - Molecule ID A0802

geneAKAP12, AKAP250
nameA-kinase anchor protein 12
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AKA12_HUMANQ02952ENSG000001310169590Hs.371240604698

Functions and classifications

GOC:cell cortex, C:cytoplasm, C:cytoskeleton, C:plasma membrane, F:protein kinase A binding, P:G-protein coupled receptor signaling pathway, P:positive regulation of cAMP biosynthetic process, P:positive regulation of protein kinase A signaling, P:protein targeting, P:regulation of protein kinase C signaling, P:signal transduction, P:positive regulation of protein kinase A signaling cascade
UniProtAlternative splicing, Complete proteome, Cytoplasm, Cytoskeleton, Lipoprotein, Myristate, Phosphoprotein, Polymorphism, Reference proteome, Repeat
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26175278aHomo sapiens16colon_rectumCRC (Stage II) (CRC)0.759945571<0.05LC-MS/MS26175278
Exp26175278bHomo sapiens10colon_rectumCRC (Stage IIIA) (CRC)0.849039972<0.05LC-MS/MS26175278
Exp26175278cHomo sapiens14colon_rectumCRC (Stage IIIB) (CRC)0.849039972<0.05LC-MS/MS26175278
Exp26175278dHomo sapiens17colon_rectumCRC (Stage IIIC) (CRC)1.314118346<0.05LC-MS/MS26175278
Exp26245529aHomo sapiens26colon_rectumAdenoma (Adenoma) 1.13E-08LC-MS/MS26245529
Exp26245529cHomo sapiens8colon_rectumColorectal cancer (CRC) (CRC) 2.17E-05LC-MS/MS26245529

Compile date 10-20-2017© .