MoCadb-logoMoCadb - Molecule ID A0143

geneAKAP5, AKAP79
nameA-kinase anchor protein 5
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AKAP5_HUMANP24588ENSG000001798419495Hs.656683604688

Functions and classifications

GOC:cytosol, C:plasma membrane, F:protein kinase A binding, P:energy reserve metabolic process, P:positive regulation of cAMP biosynthetic process, P:positive regulation of protein kinase A signaling, P:protein targeting, P:regulation of insulin secretion, P:signal transduction, P:small molecule metabolic process, P:synaptic transmission, C:asymmetric synapse, C:basolateral plasma membrane, C:dendrite membrane, C:dendritic shaft, C:dendritic spine membrane, C:filopodium membrane, C:neuronal cell body, C:perinuclear region of cytoplasm, C:postsynaptic density, C:protein complex, P:cellular protein complex disassembly, P:cellular response to chemical stimulus, P:hippocampus development, P:maternal process involved in female pregnancy, P:negative regulation of potassium ion transport, P:positive regulation of calcium ion transport into cytosol, P:positive regulation of dendrite morphogenesis, P:positive regulation of NFAT protein import into nucleus, P:positive regulation of protein kinase A signaling cascade, P:positive regulation of protein phosphorylation, P:response to electrical stimulus, P:response to muscle activity, P:spinal cord development
UniProt3D-structure, Calmodulin-binding, Complete proteome, Lipoprotein, Membrane, Palmitate, Polymorphism, Reference proteome
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp24687888aHomo sapiens33polyp_and_tumormembrane FractionsCRC without metastasis (CRC)0.42910080.017005045LC-MS/MS24687888
Exp24687888bHomo sapiens32polyp_and_tumormembrane FractionsCRC metastasis (CRC)0.4810262370.011301653LC-MS/MS24687888
Exp26245529bHomo sapiens26colon_rectum Colorectal cancer (CRC) (CRC) 4.16E-05LC-MS/MS26245529
Exp26245529cHomo sapiens8colon_rectum Colorectal cancer (CRC) (CRC) 7.75E-07LC-MS/MS26245529

Compile date 10-20-2017© .