|Welcome to MoCadb|
The Multi-Omics Cancer database MoCadb is an integrated and clustered information resource that covers multi-omic studies (microRNA, genomics, proteomics and metabolomics) of gastro-intestinal cancers with special emphasis on the colorectal neoplasms.
This resource was built by mining the existing literature and afterwards was performed a manual curation of the collected data. In order to deal with the high heterogeneity and diversity of the gathered data, a specific ontology was applied to tie together and harmonise multi-level omic studies based on gene and protein clusters (CluSO) and mapping of orthologous genes (OMAP) across species.
This database was intentionally built to allow disease pathway analysis by data-driven using a system approach, which is much more amenable and has a greater potential to provide an unbiased and novel testable hypothesis as an end-result.
The MoCadb database is a pure exploratory exercise developed as a NoSQL database for handling 'Omics datasets. The database will incorporate existing knowledge gathered from publications and other public databases, in order to yield biological meaning by integrating all available information and therefore has the potential to unravel and allow an in-depth understanding of the key molecular events that modulate cancer onset and progression.
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|No. of unique (non-redundant) molecules: 8640||Total no. of samples in Demographics file: 53|
|Total no. of studies in Study reference file/table: 377||No. of unique samples in Demographics file: 53|
|Total no. of molecule entries (redundant): 18407||Total no. of unique studies: 52|