PADB-logoLSSR - dataset 16507876

PubMed ID16507876
AuthorsCheng D, Hoogenraad CC, Rush J, Ramm E, Schlager MA, Duong DM, Xu P, Wijayawardana SR, Hanfelt J, Nakagawa T, Sheng M, Peng J.
TitleRelative and absolute quantification of postsynaptic density proteome isolated from rat forebrain and cerebellum
JournalMol Cell Proteomics. 2006 Jun;5(6):1158-70. Epub 2006 Feb 28
AbstractThe postsynaptic density (PSD) of central excitatory synapses is essential for postsynaptic signaling, and its components are heterogeneous among different neuronal subtypes and brain structures. Here we report large scale relative and absolute quantification of proteins in PSDs purified from adult rat forebrain and cerebellum. PSD protein profiles were determined using the cleavable ICAT strategy and LC-MS/MS. A total of 296 proteins were identified and quantified with 43 proteins exhibiting statistically significant abundance change between forebrain and cerebellum, indicating marked molecular heterogeneity of PSDs between different brain regions. Moreover we utilized absolute quantification strategy, in which synthetic isotope-labeled peptides were used as internal standards, to measure the molar abundance of 32 key PSD proteins in forebrain and cerebellum. These data confirm the abundance of calcium/calmodulin-dependent protein kinase II and PSD-95 and reveal unexpected stoichiometric ratios between glutamate receptors, scaffold proteins, and signaling molecules in the PSD. Our data also demonstrate that the absolute quantification method is well suited for targeted quantitative proteomic analysis. Overall this study delineates a crucial molecular difference between forebrain and cerebellar PSDs and provides a quantitative framework for measuring the molecular stoichiometry of the PSD.

SpeciesTissue / SourceSubcellDiseaseSample digestSeparationDetectionQuantification
ratbrainPSD (forebrain and cerebellum)healthytrypsin, in-gelSCXLC-MS/MS, ICAT 

Identified molecules

Molecule IDReferenceGene/SymbolNameSource acc#Regulation in diseaseRatio (disease/control)Frequency % found in diseaseFrequency % found in healthyAssociated diseaseBiomarkerNID stats
A0913CDK16_HUMAN PCTAIRE protein kinaseNP_001004132       Identified peptides: 1
A3561NDUS1_HUMANNDUFS1NADH dehydrogenase Fe-S protein 1NP_001005550       Identified peptides: 3
A3590OMGP_HUMANOMG, OMGPoligodendrocyte-myelin glycoproteinNP_001005898       Identified peptides: 1
A0418CAPZB_HUMANCAPZBF-actin capping protein betaNP_001005903       Identified peptides: 3
A3540TCPB_HUMANCCT2, 99D8.1, CCTBchaperonin containing TCP1 betaNP_001005905       Identified peptides: 1
A3677QCR2_HUMANUQCRC2ubiquinol-cytochrome c reductase core protein IINP_001006971       Identified peptides: 1
A5183TBA4A_HUMANTUBA4A, TUBA1, TUBA4tubulin alpha 4NP_001007005       Identified peptides: 9
A0154ITPR1_HUMANITPR1, INSP3R1inositol 1,4,5-triphosphate receptorNP_001007236       Identified peptides: 8
A9550RL23_HUMANRPL23ribosomal protein L23NP_001007600       Identified peptides: 1
A3957MTX2_HUMANMTX2metaxin 2NP_001008287       Identified peptides: 1
A287CPITM1_HUMANPITPNM1, DRES9, NIR2Nir2, phosphatidylinositol transfer proteinNP_001008370       Identified peptides: 1
A0235ARP2_HUMANACTR2, ARP2Arp2 homologNP_001009268       Identified peptides: 1
A8795FXL16_HUMANFBXL16, FBL16, CG14134F-box and leucine-rich repeat protein 16NP_001009504       Identified peptides: 1
A318ESHLB2_HUMANSH3GLB2, PP578, PP9455SH3-domain GRB2-like endophilin B2NP_001009692       Identified peptides: 1
A3517SEPT4_HUMANSEPT4, ARTS, PNUTL2septin 4NP_001011893       Identified peptides: 1
A5150SPTA1_HUMANSPTA1, SPTAspectrin alpha 1, erythroidNP_001011908       Identified peptides: 8
A0403VA0D1_HUMANATP6V0D1, ATP6D, VPATPDATPase, H+ transporting, V0 subunit DNP_001011927       Identified peptides: 1
A6721HEXB_HUMANHEXB, HCC7hexosaminidase BNP_001011946       Identified peptides: 2
A0401VATC1_HUMANATP6V1C1, ATP6C, ATP6DATPase, H+ transporting, V1 subunit CNP_001011992       Identified peptides: 1
A7647QORL1_HUMANCRYZL1, 4P11crystallin, zeta (quinone reductase)-like 1NP_001013062       Identified peptides: 1
A4307DNJB4_HUMANDNAJB4, DNAJW, HLJ1DnaJ (Hsp40) homolog, subfamily B, member 4NP_001013094       Identified peptides: 1
A0010SPTB2_HUMANSPTBN1, SPTB2, RPL23AP13spectrin beta 2NP_001013148       Identified peptides: 7
A9532PCBP2_HUMANPCBP2poly(rC) binding proteinNP_001013241       Identified peptides: 1
A9485SRPRB_HUMANSRPRB, APMCF1signal recognition particle receptorNP_001013270       Identified peptides: 1
A7785SCPDL_HUMANSCCPDH, CGI-49hypothetical protein LOC305021NP_001014007       Identified peptides: 1
A5336FV1_MOUSEFv1hypothetical protein LOC308568NP_001014040       Identified peptides: 1
A5348GPC4_HUMANGPC4, UNQ474/PRO937, UNQ474hypothetical LOC317322NP_001014130       Identified peptides: 1
A1019PHYIP_HUMANPHYHIP, DYRK1AP3phytanoyl-CoA hydroxylase interacting proteinNP_001017376       Identified peptides: 2
A0587ADDB_HUMANADD2, ADDBadducin betaNP_036623       Identified peptides: 1
A1923ALDOA_HUMANALDOA, ALDAfructose-bisphosphate aldolase aNP_036627       Identified peptides: 1
A0110APC_HUMANAPC, DP2.5adenomatosis polyposis coliNP_036631       Identified peptides: 1
A0342AT1A3_HUMANATP1A3ATPase, Na+/K+ transporting, alphaNP_036638       Identified peptides: 1
A1853KCC2D_HUMANCAMK2D, CAMKDCaMK II deltaNP_036651       Identified peptides: 4
A3693KCRB_HUMANCKB, CKBBcreatine kinase, brainNP_036661       Identified peptides: 3
A0493CXA1_HUMANGJA1, GJALconnexin 43NP_036699       Identified peptides: 2
A3680DHE3_HUMANGLUD1, GLUDglutamate dehydrogenaseNP_036702       Identified peptides: 1
A0003NMDE2_HUMANGRIN2B, NMDAR2BNMDAR2BNP_036706       Identified peptides: 4
A0374NFH_HUMANNEFH, NFHneurofilament triplet H proteinNP_036739       Identified peptides: 2
A0259KPCG_HUMANPRKCG, PKCGprotein kinase C gammaNP_036760       Identified peptides: 10
A4012PRIO_HUMANPRNP, PRIP, PRPprion proteinNP_036763       Identified peptides: 1
A1533SPRC_HUMANSPARC, ONsecreted acidic cysteine rich glycoproteinNP_036788       Identified peptides: 2
A3801EF1A2_HUMANEEF1A2, EEF1AL, STNtranslation elongation factor 1NP_036792       Identified peptides: 1
A1218THY1_HUMANTHY1Thy-1NP_036805       Identified peptides: 2
A9143VISL1_HUMANVSNL1, VISL1visinin-like Ca2+-binding protein type 1NP_036818       Identified peptides: 1
A0168KPCB_HUMANPRKCB1, PRKCB, PKCBprotein kinase C betaNP_036845       Identified peptides: 3
A0993KCC4_HUMANCAMK4, CAMK, CAMK-GRCaMK IVNP_036859       Identified peptides: 1
A3553CN37_HUMANCNPcyclic nucleotide phosphodiesterase 1NP_036941       Identified peptides: 3
A1073CNTN2_HUMANCNTN2, AXT, TAG1contactin 2NP_037016       Identified peptides: 2
A0556AT2A3_HUMANATP2A3ATPase, Ca++ transporting, ubiquitousNP_037046       Identified peptides: 1
A3556PGCB_HUMANBCAN, BEHAB, CSPG7brevicanNP_037048       Identified peptides: 5
A3474CA2D1_HUMANCACNA2D1, CACNL2A, CCHL2ACacna2d1, Ca++ channelNP_037051       Identified peptides: 1
A0011KCC2A_HUMANCAMK2A, CAMKACaMK II alphaNP_037052       Identified peptides: 8
A1630CD59_HUMANCD59, MIC11, MIN1CD59 glycoproteinNP_037057       Identified peptides: 1
A3608DPYL3_HUMANULIP, DPYSL3, LCRMPdihydropyrimidinase-like 3NP_037066       Identified peptides: 1
A03611433Z_HUMANYWHAZ14-3-3 protein zetaNP_037143       Identified peptides: 1
A0238STXB1_HUMANSTXBP1, UNC18A, stxbp1syntaxin binding protein 1NP_037170       Identified peptides: 2
A1074TENR_HUMANTNRtenascin-R, janusinNP_037177       Identified peptides: 2
A06331433F_HUMANYWHAH, YWHA114-3-3 protein etaNP_037184       Identified peptides: 1
A09071433T_HUMANYWHAQ14-3-3 protein tauNP_037185       Identified peptides: 3
A4043PP1B_HUMANPPP1CB, PPCS1Dphosphatase pp1 betaNP_037197       Identified peptides: 6
A0134MTAP2_HUMANMAP2, 4R-MAP2MAP 2NP_037198       Identified peptides: 2
A0093PTPRZ_HUMANPTPRZ1, HTPZP2, PTPRZphosphatase, tyrosine phosphatase zetaNP_037212       Identified peptides: 1
A0344AT1B1_HUMANATP1B1, ATP1BATPase, Na+/K+ transporting, betaNP_037245       Identified peptides: 3
A0054GNAI1_HUMANGNAI1G protein, alpha inhibiting 1NP_037277       Identified peptides: 2
A0423AATM_HUMANGOT2glutamate oxaloacetate transaminase 2NP_037309       Identified peptides: 2
A0052GNAZ_HUMANGNAZG protein, G(z), alpha subunitNP_037321       Identified peptides: 3
A3166MYH9_HUMANMYH9myosin heavy chain, nonmuscle type aNP_037326       Identified peptides: 2
A3876ADDA_HUMANADD1, ADDAadducin alphaNP_058686       Identified peptides: 1
A0331G3P_HUMANGAPD, GAPDHglyceraldehyde 3-phosphateNP_058704       Identified peptides: 1
A0001NMDZ1_HUMANhNMDAR1-4b, hNMDAR1-3b, GRIN1NMDAR1NP_058706       Identified peptides: 1
A0103GRM1_HUMANGRM1, GPRC1A, MGLUR1mGluR1NP_058707       Identified peptides: 1
A0350MBP_HUMANMBPmyelin basic proteinNP_058722       Identified peptides: 1
A0424GLNA_HUMANGLUL, GLNS, PIG43glutamine synthetase 1NP_058769       Identified peptides: 5
A3694THIL_HUMANACAT1, ACAT, MATacetyl-coenzyme A acetyltransferase 1NP_058771       Identified peptides: 1
A7232OGT1_HUMANOGT, HRNT1O linked N-acetylglucosamine transferaseNP_058803       Identified peptides: 1
A0999COF1_HUMANCFL1, CFLcofilinNP_058843       Identified peptides: 1
A1021CSRP1_HUMANCSRP1, CSRP, CYRPcysteine and glycine-rich protein 1NP_058844       Identified peptides: 1
A8138UCHL1_HUMANUCHL1, PGP 9.5, PGP9.5ubiquitin carboxy-terminal hydrolase L1NP_058933       Identified peptides: 1
A3572LSAMP_HUMANLSAMP, IGLON3, LAMPlimbic system-associated membrane proteinNP_058938       Identified peptides: 2
A3804EF2_HUMANEEF2, EF2translation elongation factor 2NP_058941       Identified peptides: 2
A0686AP1B1_HUMANAP1B1, ADTB1, BAM22AP-1 betaNP_058973       Identified peptides: 3
A3750TXTP_HUMANSLC25A1, SLC20A3solute carrier family 25, member 1NP_059003       Identified peptides: 1
A0043GNAO_HUMANGNAO1G protein, G(o), alpha subunitNP_059023       Identified peptides: 2
A3887NTRI_HUMANHNT, NTM, IGLON2neurotriminNP_059050       Identified peptides: 1
A8835HPCL1_HUMANHPCAL1, BDR1visinin-like Ca2+-binding protein type 3NP_059052       Identified peptides: 2
A0292AINX_HUMANINA, NEF5internexinNP_062001       Identified peptides: 2
A0285BSN_HUMANBSN, ZNF231bassoonNP_062019       Identified peptides: 11
A3904SYN2_HUMANsyn2, SYN2synapsin 2NP_062032       Identified peptides: 2
A5153SPTN2_HUMANSPTBN2, SCA5spectrin beta 3NP_062040       Identified peptides: 6
A3893HPLN1_HUMANHAPLN1, CRTL1proteoglycan link proteinNP_062062       Identified peptides: 3
A1191CTBP1_HUMANCTBP1, CTBPC-terminal binding protein (CtBP)NP_062074       Identified peptides: 2
A0133DYHC1_HUMANDYNC1H1, Dnchc1, DHC1dynein heavy chainNP_062099       Identified peptides: 1
A0119CLH1_HUMANCLTC, CLH17, CLTCL2clathrin heavy chainNP_062172       Identified peptides: 5
A8479RGS8_HUMANRGS8RGS8NP_062217       Identified peptides: 2
A3903SRCN1_HUMANSRCIN1, SNIP, P140SNAP-25-interacting proteinNP_062251       Identified peptides: 2
A0387ATP5H_HUMANATP5H, My032mitochondrial F0 complex, subunit dNP_062256       Identified peptides: 1
A0013DLG4_HUMANDLG4, PSD95, TIP15PSD-95/SAP90NP_062567       Identified peptides: 2
A0568PCLO_HUMANPCLO, ACZpiccoloNP_064483       Identified peptides: 1
A0074SHAN3_HUMANSHANK3, PSAP2, PROSAP2Shank 3NP_067708       Identified peptides: 1
A3888NEGR1_HUMANNEGR1, IGLON4, UNQ2433/PRO4993kilonNP_067714       Identified peptides: 3
A1851KCC2B_HUMANCAMK2B, CAM2, CAMKBCaMK II betaNP_068507       Identified peptides: 5
A0117NSF_HUMANNSFNSF, N-ethylmaleimide sensitive factorNP_068516       Identified peptides: 2
A3900LIN7C_HUMANLIN7C, MALS3, VELI3lin-7 homolog CNP_068623       Identified peptides: 1
A4461FXYD5_HUMANFXYD5, DYSAD, IWU1FXYD domain-containing ion transport regulator 5NP_068709       Identified peptides: 1
A0149MYO5A_HUMANMYO5A, MYH12myosin VNP_071514       Identified peptides: 2
A0014DLG2_HUMANDLG2PSD-93/chapsyn-110NP_071618       Identified peptides: 1
A5178TBA1A_HUMANTUBA1A, TUBA3tubulin alpha 1NP_071634       Identified peptides: 10
A1941PLEC_HUMANPLEC1, PLECplectinNP_071796       Identified peptides: 1
A3807RLA0_HUMANRPLP0ribosomal protein LA0NP_071797       Identified peptides: 1
A4042PP1G_HUMANPPP1CCphosphatase pp1 gammaNP_071943       Identified peptides: 6
A3808RL4_HUMANRPL4, RPL1ribosomal protein L4NP_071955       Identified peptides: 1
A4051AAKB2_HUMANPRKAB2protein kinase, AMP-activated, beta 2NP_072149       Identified peptides: 1
A0351MOG_HUMANMOGmyelin-oligodendrocyte glycoproteinNP_073159       Identified peptides: 2
A9560RL30_HUMANRPL30ribosomal protein L31NP_073190       Identified peptides: 2
A4582ARL3_HUMANARL3, ARFL3Arf-like 3NP_073191       Identified peptides: 1
A0637GEPH_HUMANGPHRYN, GPHN, GPHgephyrinNP_074056       Identified peptides: 1
A0433TPIS_HUMANTPI1, TPI, TIMtriosephosphate isomerase 1NP_075211       Identified peptides: 4
A3536DNJA1_HUMANDNAJA1, DNAJ2, HDJ2DnaJ-like protein 2NP_075223       Identified peptides: 1
A0107DLGP1_HUMANDLGAP1, DAP1, GKAPGKAP/SAPAP-1NP_075235       Identified peptides: 1
A0328GRID2_HUMANGRID2, GLURD2GluRd, glutamate receptor deltaNP_077355       Identified peptides: 4
A6308DHB4_HUMANHSD17B4, EDH17B4estradiol 17 beta-dehydrogenase 4NP_077368       Identified peptides: 2
A5099PROF2_HUMANPFN2profilin 2NP_110500       Identified peptides: 1
A0069GBB1_HUMANGNB1G protein g(i)/g(s)/g(t) beta subunit 1NP_112249       Identified peptides: 3
A0352MYPR_HUMANPLP1, PLPmyelin proteolipid proteinNP_112252       Identified peptides: 2
A0085MAP1A_HUMANMAP1A, MAP1L, M1LPMAP 1aNP_112257       Identified peptides: 2
A0252AP2A2_HUMANAP2A2, ADTAB, CLAPA2AP-2 alpha 2NP_112270       Identified peptides: 2
A9848CSK2B_HUMANCSNK2B, CK2N, G5Acasein kinase 2 betaNP_112283       Identified peptides: 3
A0603GABR1_HUMANGABBR1, GPRC3AGABA B receptor 1NP_112290       Identified peptides: 1
A0055GNAI2_HUMANGNAI2, GNAI2BG protein, alpha inhibiting 2NP_112297       Identified peptides: 3
A0070GBB2_HUMANGNB2G protein, beta 2NP_112299       Identified peptides: 2
A3612IP3KA_HUMANITPKAinositol 1,4,5-trisphosphate 3-kinase ANP_112307       Identified peptides: 2
A0324PLAK_HUMANJUP, CTNNG, DP3catenin delta family, plakoglobinNP_112309       Identified peptides: 3
A3813RL10A_HUMANRPL10A, NEDD6ribosomal protein L10ANP_112327       Identified peptides: 1
A1300DGKZ_HUMANDGKZ, DAGK6diacylglycerol kinase zetaNP_112405       Identified peptides: 1
A4548ACTB_HUMANACTB, PS1TP5BP1actin betaNP_112406       Identified peptides: 6
A3696MDHM_HUMANMDH2malate dehydrogenase, mitochondrialNP_112413       Identified peptides: 2
A4745DBNL_HUMANDBNL, CMAP, SH3P7drebrin-likeNP_112642       Identified peptides: 1
A3479VDAC3_HUMANVDAC3porin 3, voltage dependent anion channelNP_112645       Identified peptides: 2
A0201RASK_HUMANK-ras, K-RAS, KRASRas family, K-Ras-2NP_113703       Identified peptides: 1
A3961MYH10_HUMANMYH10, Smembmyosin heavy chain, nonmuscle type bNP_113708       Identified peptides: 2
A3884NCAM1_HUMANNCAM1, NCAMNCAM-140NP_113709       Identified peptides: 1
A0147PP1A_HUMANPPP1CA, PPP1Aphosphatase pp1 alphaNP_113715       Identified peptides: 6
A0414VPP1_HUMANATP6V0A1, ATP6N1, ATP6N1AATPase, H+ transporting, V0 subunit ANP_113792       Identified peptides: 1
A0296GRIA1_HUMANGRIA1, GLUR1, GLUH1GluR1NP_113796       Identified peptides: 1
A0016DLG3_HUMANDLG3SAP102NP_113827       Identified peptides: 1
A3892NCAN_HUMANNCAN, CSPG3, NEURchondroitin sulfate proteoglycan 3NP_113841       Identified peptides: 3
A6692HCD2_HUMANHSD17B10, ERAB, HADH2hydroxyacyl-Coenzyme A dehydrogenaseNP_113870       Identified peptides: 1
A0104HOME1_HUMANHOMER1, SYN47Homer 1NP_113895       Identified peptides: 1
A0075SHAN1_HUMANSHANK1Shank 1NP_113939       Identified peptides: 1
A0073GBB5_HUMANGNB5G protein, beta 5NP_113958       Identified peptides: 1
A0515GUAD_HUMANGAH, GDAguanine deaminaseNP_113964       Identified peptides: 1
A3532GIT1_HUMANGIT1ArfGAP, GIT1NP_114002       Identified peptides: 1
A0758CNTP1_HUMANCNTNAP1, CASPR, NRXN4neurexin IV, paranodinNP_114450       Identified peptides: 3
A0214KALRN_HUMANKALRN, DUET, DUOkalirin, RhoGEF kinase NP_114451       Identified peptides: 2
A949BEAA4_HUMANSLC1A6, EAAT4glutamate transporter, high affinityNP_114454       Identified peptides: 2
A3535DNJA2_HUMANDNAJA2, CPR3, HIRIP4DnaJ (Hsp40) homolog, subfamily A, member 2NP_114468       Identified peptides: 1
A0222GSK3B_HUMANGSK3Bglycogen synthase kinase 3 betaNP_114469       Identified peptides: 1
A6992MDHC_HUMANMDH1, MDHAmalate dehydrogenase 1, NAD (soluble)NP_150238       Identified peptides: 1
A0035RIMS1_HUMANRIMS1, RAB3IP2, RIM1Rim, rab3 effectorNP_439894       Identified peptides: 1
A0105HOME2_HUMANHOMER2Homer 2NP_445761       Identified peptides: 1
A0514DYL1_HUMANDNCL1, DYNLL1, DLC1dynein light chainNP_445771       Identified peptides: 1
A0112CTNB1_HUMANCTNNB1, CTNNB, PRO2286catenin betaNP_445809       Identified peptides: 6
A0510NEB1_HUMANPPP1R9AF-actin binding protein, neurabin-I, NP_445925       Identified peptides: 1
A0141LIN7A_HUMANLIN7A, MALS1, VELI1lin-7 homolog ANP_445966       Identified peptides: 1
A0395ADT1_HUMANSLC25A4, ANT1solute carrier family 25, member 4NP_445967       Identified peptides: 4
A7503PRDX5_HUMANPRDX5, ACR1, SBBI10peroxiredoxin 5NP_446062       Identified peptides: 1
A9972LANC1_HUMANLANCL1, GPR69A, P40LanC-like 1NP_446175       Identified peptides: 1
A3697SUCA_HUMANSUCLG1succinate-CoA ligase alphaNP_446204       Identified peptides: 1
A0379ATPG_HUMANATP5C1, ATP5C, ATP5CL1mitochondrial F1 complex, gammaNP_446277       Identified peptides: 1
A0254AP2M1_HUMANAP2M1, CLAPM1Arp2 mu 1NP_446289       Identified peptides: 2
A0181MK01_HUMANMAPK1, ERK2, PRKM1mitogen activated protein kinase 1NP_446294       Identified peptides: 1
A3886OPCM_HUMANOPCML, IGLON1, OBCAMobcamNP_446300       Identified peptides: 1
A0663NFASC_HUMANNFASCneurofascinNP_446361       Identified peptides: 4
A3865E41L3_HUMANEPB41L3, DAL1band 4.1-like 3 NP_446379       Identified peptides: 1
A3518SEPT5_HUMANSEPT5, CDCrel-1, PNUTL1septin-like protein, CDCrel-1ANP_446383       Identified peptides: 2
A0396ADT2_HUMANSLC25A5, ANT2solute carrier family 25, member 5NP_476443       Identified peptides: 4
A0757CNTN1_HUMANCNTN1contactin 1NP_476459       Identified peptides: 3
A02952AAA_HUMANPPP2R1Aphosphatase 2 regulatory subunit ANP_476481       Identified peptides: 1
A0150LRRC7_HUMANLRRC7, LAP1densin-180NP_476483       Identified peptides: 1
A7300PARK7_HUMANPARK7, DJ-1DJ-1 proteinNP_476484       Identified peptides: 1
A0400VATB2_HUMANATP6V1B2, ATP6B2, VPP3ATPase, H+ transporting, V1 subunit BNP_476561       Identified peptides: 2
A0253AP2B1_HUMANAP2B1, ADTB2, CLAPB1AP-2 betaNP_542150       Identified peptides: 2
A0095DYN1_HUMANDNM1, DNMdynamin 1NP_542420       Identified peptides: 1
A3990CSKI1_HUMANCASKIN1cask-interacting protein 1NP_542421       Identified peptides: 3
A943BDYL2_HUMANDYNLL2, DLC2, Dlc2dynein light chain 2NP_542428       Identified peptides: 1
A0667CDK5_HUMANCDK5, CDKN5cyclin-dependent kinase 5NP_543161       Identified peptides: 1
A6970MARK3_HUMANMARK3, CTAK1, EMK2MAP/microtubule affinity-regulating kinase 3NP_570105       Identified peptides: 1
A3732DIC_HUMANSLC25A10, DICsolute carrier family 25, member 10NP_596909       Identified peptides: 1
A0081SHAN2_HUMANSHANK2, CORTBP1, PROSAP1Shank 2NP_597684       Identified peptides: 3
A0212RP3A_HUMANRPH3Arabphilin-3aNP_598202       Identified peptides: 1
A5407NDRG2_HUMANNDRG2, SYLDNDRG family member 2NP_598267       Identified peptides: 1
A1852KCC2G_HUMANCAMK2G, CAMK, CAMK-IICaMK II gammaNP_598289       Identified peptides: 5
A1176APOE_HUMANAPOEapolipoprotein ENP_620183       Identified peptides: 1
A6833KC1D_HUMANCSNK1D, HCKIDcasein kinase 1 deltaNP_620691       Identified peptides: 1
A5349GPSM1_HUMANGPSM1, AGS3G-protein signalling modulator 1NP_653346       Identified peptides: 1
A424AFHL1_HUMANFHL1, SLIM1four and a half LIM domains 1NP_663702       Identified peptides: 1
A0789BCAS1_HUMANBCAS1, AIBC1, NABC1PMES-2, actin-bindingNP_663703       Identified peptides: 1
A0440LGI1_HUMANLGI1, EPT, UNQ775/PRO1569LGI1, leucine-rich, glioma inactivated 1NP_665712       Identified peptides: 2
A5520ZWINT_HUMANZWINTSNAP25 interacting protein 30NP_671479       Identified peptides: 1
A1697NPTX1_HUMANNPTX1neuronal pentraxin, Ca++ bindingNP_714957       Identified peptides: 2
A3878RB6I2_HUMANRAB6IP2, ERC1, ELKSRab6-interacting protein 2NP_740769       Identified peptides: 1
A5151SPTN1_HUMANSPTAN1, SPTA2, NEASspectrin alpha 2NP_741984       Identified peptides: 5
A1958GSTM5_HUMANGSTM5glutathione-S-transferase, mu 5NP_742035       Identified peptides: 1
A3867E41L1_HUMANEPB41L1band 4.1-like 1NP_742087       Identified peptides: 1
A5195TBB5_HUMANTUBB, TUBB5, XTP3TPATP1tubulin beta 5NP_775125       Identified peptides: 10
A9704DLGP4_HUMANDLGAP4, DAP4, SAPAP4GKAP/SAPAP-4NP_775168       Identified peptides: 1
A1820EF1A1_HUMANEEF1A1, EEF1A, EF1Atranslation elongation factor TuNP_787032       Identified peptides: 1
A0024SYGP1_HUMANSYNGAP1synGAPNP_851606       Identified peptides: 6
A7867SRR_HUMANSRRserine racemaseNP_942052       Identified peptides: 1
A5191TBB4B_HUMANTUBB2C, TUBB4B, TUBB2tubulin beta 2NP_954525       Identified peptides: 9
A9545RL18A_HUMANRPL18Aribosomal protein L18aNP_997675       Identified peptides: 1
A5152SPTB1_HUMANHSpTB1, SPTB, SPTB1spectrin beta 1, erythroidNP_997687       Identified peptides: 6
A8449PHAR1_HUMANPHACTR1, RPEL, RPEL1phosphatase and actin regulator 1NP_999622       Identified peptides: 1
A9538RL10_HUMANRPL10, DXS648E, QMribosomal protein L10XP_212832       Identified peptides: 1
A0007ACTN2_HUMANACTN2actinin alphaXP_214499       Identified peptides: 2
A7849SPCS2_HUMANSPCS2, SPC25signal peptidase complex subunit 2XP_214994       Identified peptides: 1
A370AEFTU_HUMANTUFMtranslation elongation factor Tu, mitochondrialXP_215069       Identified peptides: 1
A3555CSPG2_HUMANVCAN, CSPG2chondroitin sulfate proteoglycan 2XP_215451       Identified peptides: 4
A0625MAP1B_HUMANMAP1BMAP 1bXP_215469       Identified peptides: 4
A3949MTCH2_HUMANMTCH2, MIMP, HSPC032mitochondrial carrier homolog 2XP_215769       Identified peptides: 2
A3528RPGF4_HUMANRAPGEF4, CGEF2, EPAC2GEFII, cAMP-regulatedXP_215985       Identified peptides: 3
A3539TCPH_HUMANCCT7, CCTH, NIP7-1chaperonin containing TCP1 etaXP_216180       Identified peptides: 1
A3994CHCH6_HUMANCHCHD6, CHCM1coiled-coil-helix-coiled-coil-helix domain containing 6XP_216212       Identified peptides: 1
A3979IGS21_HUMANIGSF21hypothetical protein MGC15730XP_216568       Identified peptides: 2
A4367PIN1_HUMANPIN1PIN 1 (peptidyl-prolyl cis/trans isomerase)XP_216609       Identified peptides: 1
A86392A5E_HUMANPPP2R5Ephosphatase 2A subunit B56 epsilonXP_216739       Identified peptides: 2
A3698CY1_HUMANCYC1cytochrome c-1XP_216944       Identified peptides: 1
A697CVPS28_HUMANVPS28, FP3517vacuolar protein sorting 28XP_216962       Identified peptides: 1
A8874LYNX1_HUMANLYNX1, SLURP2, UNQ871/PRO1889Ly-6/neurotoxin homologXP_216965       Identified peptides: 2
A4303DNJA4_HUMANDNAJA4, MST104, PRO1472DnaJ (Hsp40) homologXP_217147       Identified peptides: 1
A2139COR2B_HUMANCORO2BcoroninXP_217183       Identified peptides: 1
A0233ARPC2_HUMANARPC2, ARC34, PRO2446Arp2/3 complex subunit 2XP_217432       Identified peptides: 1
A6349DNPEP_HUMANDNPEP, ASPEP, DAPaspartyl aminopeptidaseXP_217444       Identified peptides: 1
A0420ABLM1_HUMANABLIM1, ABLIM, LIMAB1actin-binding LIM protein 1XP_217645       Identified peptides: 2
A5154SPTN4_HUMANSPTBN4, SPTBN3, SPNB4spectrin beta 4XP_218364       Identified peptides: 1
A3962MYH14_HUMANMYH14, FP17425myosin heavy chain, nonmuscle type II-CXP_218617       Identified peptides: 2
A0251AP2A1_HUMANAP2A1, ADTAA, CLAPA1AP-2 alpha 1XP_218624       Identified peptides: 2
A096ARHOG_HUMANRHOG, ARHGRas family proteinXP_218977       Identified peptides: 2
A3773GHC1_HUMANSLC25A22, GC1solute carrier family 25, member 22XP_219484       Identified peptides: 2
A5862ATAD1_HUMANATAD1ATPase family, AAA domain containingXP_220076       Identified peptides: 1
A374ETANC2_HUMANTANC2ankyrin-repeat containing proteinXP_221028       Identified peptides: 1
A4049MYL6_HUMANMYL6, MLC3nm, LC17Amyosin, light chain 6XP_222163       Identified peptides: 1
A2472ENPP6_HUMANENPP6, UNQ1889/PRO4334, UNQ1889phosphodiesterase 6XP_224853       Identified peptides: 1
A5192TBB3_HUMANTUBB3, TUBB4tubulin beta 6XP_225867       Identified peptides: 6
A0469CTND2_HUMANCTNND2, NPRAPcatenin delta, NPRAPXP_226897       Identified peptides: 1
A3653DDX3X_HUMANDDX3X, DBX, DDX3DEAD box polypeptide 3XP_228701       Identified peptides: 1
A0545NCKP1_HUMANNCKAP1, HEM2, NAP1NCK-associated protein 1XP_230038       Identified peptides: 1
A4002K154L_HUMANKIAA1549L, G2G2 proteinXP_230346       Identified peptides: 1
A0594SNPH_HUMANSNPHsyntaphilinXP_230716       Identified peptides: 1
A1914CTNA2_HUMANCTNNA2, CAPRcatenin alpha neuronal, N-cateninXP_232077       Identified peptides: 2
A009241_HUMANEPB41, E41Pband 4.1 erythrocyteXP_232771       Identified peptides: 1
A9033RPGP1_HUMANrap1GAP, RAP1GAP, RAP1GA1RAP1, GTPase activating protein 1XP_233609       Identified peptides: 1
A3870CLMN_HUMANCLMNcalmin deltaXP_234500       Identified peptides: 1
A8662ANS1B_HUMANANKS1B, EB-1cajalin 2, E2a-Pbx1-associated proteinXP_235052       Identified peptides: 3
A3960MYO6_HUMANMYO6myosin VIXP_236444       Identified peptides: 1
A245BZN451_HUMANZNF451, COASTERzinc finger protein 451XP_237039       Identified peptides: 1
A0660ACTZ_HUMANACTR1A, CTRN1Arp1 actin-related protein 1 homolog AXP_238177       Identified peptides: 1
A3558CHCH3_HUMANCHCHD3, MINOS3coiled-coil-helix-coiled-coil-helix domain containing 3XP_238346       Identified peptides: 1
A0662ANK1_HUMANhANK1, ANK1, ANKankyrin erythroidXP_240464       Identified peptides: 2
A2254FBX41_HUMANFBXO41, FBX41F-box protein 41XP_242562       Identified peptides: 1
A1157SEM7A_HUMANSEMA7A, CD108, SEMALSemaphorin 7AXP_243863       Identified peptides: 1
A4302DNJA3_HUMANDNAJA3, HCA57, TID1DnaJ (Hsp40) homolog, subfamily A, member 3XP_340756       Identified peptides: 1
A3964MY18A_HUMANMAJN, MYO18A, MYSPDZmyosin XVIIIaXP_340848       Identified peptides: 1
A0436MPP2_HUMANMPP2, DLG2MPP2, MAGUK p55 subfamily XP_340913       Identified peptides: 1
A0397VATA_HUMANATP6V1A, ATP6A1, ATP6V1A1ATPase, H+ transporting, V1 subunit AXP_340988       Identified peptides: 1
A0234ARP3_HUMANACTR3, ARP3Arp3 homologXP_341113       Identified peptides: 5
A3621SUCB1_HUMANSUCLA2succinate-CoA ligase betaXP_341355       Identified peptides: 1
A4855HPLN4_HUMANHAPLN4, BRAL2, TM6SF2cartilage link protein 1XP_341417       Identified peptides: 4
A6235CYLD_HUMANCYLD, CYLD1, HSPC057familial cylindromatosis CYLDXP_341653       Identified peptides: 2
A210CNDUB7_HUMANNDUFB7NADH dehydrogenase 1 beta subcomplexXP_341665       Identified peptides: 1
A589CSYTL2_HUMANCHR11SYT, SYTL2, SGA72Msynaptotagmin-like proteinXP_341883       Identified peptides: 1
A976CCC88B_HUMANCCDC88B, BRLZribosomal protein S6 kinaseXP_342005       Identified peptides: 1
A3873ANK2_HUMANANK2ankyrin 2XP_342338       Identified peptides: 3
A113DCI172_HUMAN Gene model 996XP_342385       Identified peptides: 1
A3339ARP3B_HUMANACTR3B, ARP4, ARP3BETAArp3 betaXP_342612       Identified peptides: 1
A2342MACF1_HUMANMACF1, ABP620, ACF7MACF, microtubule actin cross-linking factorXP_342907       Identified peptides: 1
A9540RL11_HUMANRPL11ribosomal protein L11XP_342950       Identified peptides: 1
A2119STRN3_HUMANSTRN3, GS2NA, SG2NAstriatin, calmodulin binding protein 3XP_343060       Identified peptides: 1
A1227TEBP_HUMANPTGES3, P23, TEBPunactive progesterone receptorXP_343136       Identified peptides: 1
A0605ODP2_HUMANDLAT, DLTAdihydrolipoamide S-acetyltransferaseXP_343390       Identified peptides: 1
A0307KPCA_HUMANPRKCA, PKCA, PRKACAprotein kinase C alphaXP_343976       Identified peptides: 3
A4956MA6D1_HUMANMAP6D1hypothetical protein FLJ12748XP_344040       Identified peptides: 2
A0918I5P1_HUMANINPP5Ainositol polyphosphate-5-phosphatase AXP_344972       Identified peptides: 1
A0200RASH_HUMANHRAS, H-RAS, c-bas/hasRas family, H-Ras-1XP_346330       Identified peptides: 1
A6519FN3K_HUMANFN3Kfructosamine-3-kinaseXP_573235       Identified peptides: 1
A0276CTRO_HUMANCIT, CRIK, STK21Citron, a effector molecule for RhoXP_573407       Identified peptides: 1
A218CNDUS5_HUMANNDUFS5NADH dehydrogenase Fe-S protein 5XP_573679       Identified peptides: 1
A9634RS16_HUMANRPS16ribosomal protein S16XP_574243       Identified peptides: 1
A5475TBATA_HUMANTBATA, SPATIALspatial-deltaXP_574753       Identified peptides: 1
A9541RL12_HUMANRPL12ribosomal protein L12XP_575115       Identified peptides: 2
A624AK1045_HUMAN KIAA1045 proteinXP_575808       Identified peptides: 1
A86402A5G_HUMANPPP2R5Cphosphatase 2A subunit B56 gammaXP_576101       Identified peptides: 1
A3811RL7A_HUMANRPL7A, SURF-3, SURF3ribosomal protein L7aXP_577004       Identified peptides: 3
A9577RL9_HUMANRPL9, RPL9P7, RPL9P8ribosomal protein L9XP_578123       Identified peptides: 1
A492CSCRN1_HUMANSCRN1Secernin 1XP_578274       Identified peptides: 1
A8664ARG33_HUMANARHGEF33Rab6-interacting protein 1XP_578521       Identified peptides: 3

Compile date 12-23-2014© PADB initiative