PADB-logoLSSR - molecule cluster A9987MACROD1, LRP16O-acetyl-ADP-ribose deacetylase MACROD1

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensMACD1_HUMANQ9BQ6932535505610400

Functions and Classifications

GOC:mitochondrion, C:nucleus, F:deacetylase activity, F:hydrolase activity, acting on glycosyl bonds, P:cellular response to DNA damage stimulus, P:protein de-ADP-ribosylation, P:purine nucleoside metabolic process, C:mitochondrion, P:purine nucleoside metabolic process
UniProt3D-structure, Acetylation, Chromosomal rearrangement, Complete proteome, DNA damage, Hydrolase, Nucleus, Reference proteome
PADBENZ: enzyme, enzymatic properties

Expression

percent [in mouse]
cerebrumcerebellumbrainstemspinal cordkidneyliverheartskeletal muscleadiposestomachsmall intestinelarge intestinetestisplacenta
1511137141410961344

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
18501002mousekidneycortexUnknownhealthy     
16684767humanbloodplasma severe trauma     Identified peptides: 1
18614015mousecerebrum; cerebellum; brainstem; spinal cord; kidney; liver; heart; skeletal muscle; adipose; stomach; small intestine; large intestine; testis; placentamitochondria healthy     
15253431humanheartmitochondria healthy     Unique peptides: 3
21616181mousecornea  lumican knock-out   1.17 
21170055humanbrainPSD (neocortex) Glial neoplasm/Lesional epilepsy/Colloid cyst     Unique peptides: 2
16615899mouseliverorganelleMitochondrion (Mito)healthy     

Compile date 12-23-2014© PADB initiative