PADB-logoLSSR - molecule cluster A9934HAMP, HEPC, LEAP1Hepcidin precursor

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensHEPC_HUMANP81172849408606464, 613313

Functions and Classifications

GOC:apical cortex, C:extracellular region, P:cellular iron ion homeostasis, P:defense response to bacterium, P:defense response to fungus, P:immune response, P:killing of cells of other organism
UniProt3D-structure, Antibiotic, Antimicrobial, Cleavage on pair of basic residues, Complete proteome, Direct protein sequencing, Disease mutation, Disulfide bond, Fungicide, Hormone, Reference proteome, Secreted, Signal
PADBSIG: signalling

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
16948836humanurinewhole healthy     
17272487humanbloodserum healthy     m/z: 2788.45
16691549ratliverGolgi healthy      
16281181humanurinewhole healthy     
17272487humanurinewhole healthy     m/z: 2788.45
18558005humanurinewhole colorectal cancer     m/z: 2433
16621968humanurinewhole renal anemia, hemodialysis  highly upregulated   
16621968humanurinewhole renal anemia, hemodialysis  highly upregulated   
18558005humanurinewhole colorectal cancer   0.67 
18558005humanurinewhole colorectal cancer   0.53 
18558005humanurinewhole colorectal cancer     m/z: 2788
18440303raturineglycoproteinssecreatedglomerular disease/adriamycin nephropathy and Thy1.1 glomerulonephritis   0.00
21127740humanurinewhole acute abdominal pain     Identified peptides: 6

Compile date 12-23-2014© PADB initiative