PADB-logoLSSR - molecule cluster A986ASBDS, CGI-97, SBDSPRibosome maturation protein SBDS

Molecule reference

organismSwissProtUniProtlength [aa]Mr [Da]OMIM
Homo sapiensSBDS_HUMANQ9Y3A525028763260400, 607444

Functions and Classifications

GOC:cytoplasm, C:nucleolus, C:nucleoplasm, C:spindle pole, F:microtubule binding, F:ribosome binding, F:rRNA binding, P:bone marrow development, P:bone mineralization, P:cell proliferation, P:inner cell mass cell proliferation, P:leukocyte chemotaxis, P:mature ribosome assembly, P:mitotic spindle stabilization, P:ribosomal large subunit biogenesis, P:rRNA processing
UniProt3D-structure, Acetylation, Complete proteome, Cytoplasm, Cytoskeleton, Direct protein sequencing, Disease mutation, Nucleus, Reference proteome, Ribosome biogenesis
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Expression

ratios [in rat]
cytosol/nucleusheart/brainkidney/brainliver/brain
 0.910.850.71

tissues and studies

study IDspeciestissuesubfractionsubcellular locationdiseaseassociated diseasebiomarkerregulation in diseaseratio (disease/control)frequency %study and detectID stats
21616181mousecornea  lumican knock-out   0.85 
17172703humanmultiplemitochondriaMitochondrialhealthy     detection: high confidence prediction (Mitopred)confidence %: 99
16928776ratbrain;heart;kidney;livermitochondria healthy      
16381850humanHela cell extractnucleus healthy     theoretical Mr: 29030
16615899mouseliverorganelle healthy     
15951573humanlungbronchoalveolar lavage asthma     
UNPUBLISHED_3humanPC3 cancer cellwhole        

Compile date 12-23-2014© PADB initiative